Results 61 to 70 of about 1,558,588 (319)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Multispectral Image Enhancement Based on the Dark Channel Prior and Bilateral Fractional Differential Model

open access: yesRemote Sensing, 2022
Compared with single-band remote sensing images, multispectral images can obtain information on the same target in different bands. By combining the characteristics of each band, we can obtain clearer enhanced images; therefore, we propose a ...
Weijie Chen   +3 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Advanced Progress of Optical Wireless Technologies for Power Industry: An Overview

open access: yesApplied Sciences, 2020
Optical wireless communications have attracted widespread attention in the traditional power industry because of the advantages of large spectrum resources, strong confidentiality, and freedom from traditional electromagnetic interference.
Jupeng Ding   +4 more
doaj   +1 more source

Adaptive detection with bounded steering vectors mismatch angle [PDF]

open access: yes, 2007
We address the problem of detecting a signal of interest (SOI), using multiple observations in the primary data, in a background of noise with unknown covariance matrix.
Besson, Olivier
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Frontier Progress of Unmanned Aerial Vehicles Optical Wireless Technologies

open access: yesSensors, 2020
With the continuous maturity of unmanned aerial vehicles (UAV) in materials, communications, and other related technologies, the UAV industry has developed rapidly in recent years.
Jupeng Ding   +4 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Using Spreadsheets to Teach Signal Detection Theory [PDF]

open access: yes, 2014
Signal detection theory (SDT) is a mathematical framework for evaluating the performance of a detection system, which is broadly applicable across many academic and practical domains, including medicine, psychology, statistics and engineering.
Christopher R Fisher
core  

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