Results 91 to 100 of about 2,880,447 (285)
Signal Integrity Applications of an EBG Surface
Electromagnetic band-gap (EBG) surfaces have found applications in mitigation of parallel-plate noise that occurs in high speed circuits. A 2D periodic structure previously introduced by the same authors is dimensioned here for adjusting EBG parameters
MATEKOVITS, L., DE SABATA, A.
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
XML Data Integrity Based on Concatenated Hash Function [PDF]
Data integrity is the fundamental for data authentication. A major problem for XML data authentication is that signed XML data can be copied to another document but still keep signature valid. This is caused by XML data integrity protecting.
Lu, Joan, Liu, Baolong, Yip, Yau Jim
core +2 more sources
Analysis of Simulation Optimization for High-Speed Digital Interface Topology
Signal integrity in communication systems is becoming increasingly severe with the widespread adoption of buses with high-speed digital interfaces, since this issue potentially leads to sporadic stalls or crashes in the systems.
LI Ming, KUANG Fen
doaj
Hybrid EBG Structure for Common-Mode Noise and SSN Suppression in Multilayer PCBs
The advancement of modern technologies and the growing demand for high-speed communication systems that integrate digital and analog circuits into multilayer printed circuit boards (PCBs) require the development of efficient solutions to ensure signal ...
Jean Carlos Bortoli Dalcin +1 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

