Results 111 to 120 of about 337,357 (338)

Platform-based design, test and fast verification flow for mixed-signal systems on chip

open access: yes, 2011
This research is providing methodologies to enhance the design phase from architectural space exploration and system study to verification of the whole mixed-signal system.
CECCHINI, TOMMASO
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Navigation and Positioning Methods Using Signal of Opportunity of Low Earth Orbit Satellites

open access: yes天地一体化信息网络
In recent years, low earth orbit (LEO) giant constellations have developed rapidly, and their main goal is to provide users with high-speed Internet services.
ZHANG Yichao   +6 more
doaj  

Experimental verification of passive radar space object detection with a single low‐frequency array radio telescope

open access: yesIET Radar, Sonar & Navigation
The paper focuses on the results of experimental research on the possibility of passive space object detection using a single radio telescope from the European Low‐Frequency Array (LOFAR) network of astronomical radio telescopes.
Konrad Jędrzejewski   +3 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Signals of Opportunity for Positioning Purposes

open access: yes, 2019
O ver the last years, location-based services (LBS) have become popular due to the emergence of smartphones with capabilities of positioning their user’s location on Earth at unprecedented speed and convenience. Behind such feat are the technological advances in global navigation satellite systems (GNSS), such as Galileo, Globalnaya Navigazionnaya ...
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Multi-Frequency Target Detection Techniques for DVB-T Based Passive Radar Sensors

open access: yesSensors, 2016
This paper investigates the possibility to improve target detection capability in a DVB-T- based passive radar sensor by jointly exploiting multiple digital television channels broadcast by the same transmitter of opportunity.
Tatiana Martelli   +3 more
doaj   +1 more source

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