Results 11 to 20 of about 260,297 (259)
Considering the problem of GNSS service interruption caused by the insufficient number of available satellites in complex environments, Low Earth Orbit (LEO) satellites can supplement GNSS effectively.
Muyuan Jiang +4 more
doaj +1 more source
S1P signaling: new therapies and opportunities [PDF]
Development of sphingosine-1-phosphate receptor 1 (S1P1) modulators to dampen inflammation and its sequelae is becoming increasingly promising for treating medical conditions characterized by significant immunopathology. As shown by the non-selective S1P receptor modulator FTY720 (fingolimod [Gilenya(®)]) in the treatment of relapsing-remitting ...
Gonzalez-Cabrera, Pedro J. +3 more
openaire +2 more sources
WNT signalling: mechanisms and therapeutic opportunities [PDF]
This themed section of the British Journal of Pharmacology stems from the EMBO Conference: Wnt Meeting 2016 held from the 14th to 16th September 2016 in Brno, Czech Republic.Linked ArticlesThis article is part of a themed section on WNT Signalling: Mechanisms and Therapeutic Opportunities.
Gunnar, Schulte, Vitezslav, Bryja
openaire +2 more sources
WNT signaling in glioblastoma and therapeutic opportunities [PDF]
WNTs and their downstream effectors regulate proliferation, death, and migration and cell fate decision. Deregulation of WNT signaling is associated with various cancers including GBM, which is the most malignant primary brain cancer. In this review, we will summarize the experimental evidence supporting oncogenic roles of WNT signaling in GBM and ...
Yeri, Lee +4 more
openaire +2 more sources
Automated Histology Analysis: Opportunities for signal processing [PDF]
Histology is the microscopic inspection of plant or animal tissue. It is a critical component in diagnostic medicine and a tool for studying the pathogenesis and biology of processes such as cancer and embryogenesis. Tissue processing for histology has become increasingly automated, drastically increasing the speed at which histology labs can produce ...
Michael T. McCann +4 more
openaire +1 more source
Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities [PDF]
AbstractNeurodegenerative diseases are characterised by progressive damage to the nervous system including the selective loss of vulnerable populations of neurons leading to motor symptoms and cognitive decline. Despite millions of people being affected worldwide, there are still no drugs that block the neurodegenerative process to stop or slow disease
Marlene F. Schmidt +3 more
openaire +3 more sources
Do subseasonal forecasts take advantage of Madden–Julian oscillation windows of opportunity?
This study proposes an objective methodology to highlight windows of opportunity in a numerical subseasonal forecasting system. The methodology is based on a contingency table and is applied to the prediction of heavy tropical precipitation by the ...
Damien Specq, Lauriane Batté
doaj +1 more source
Since Global Navigation Satellite Systems (GNSS) show degraded performance in dense urban and indoor areas, a positioning sensor based on Digital Video Broadcast-Terrestrial (DVB-T) systems is presented in this paper.
Letizia Lo Presti +2 more
doaj +1 more source
Signals Of Opportunity In Mobile Radio Positioning
Publication in the conference proceedings of EUSIPCO, Bucharest, Romania ...
Dammann, Armin +2 more
openaire +4 more sources
A Model of Smiling as a Costly Signal of Cooperation Opportunities [PDF]
We develop a theoretical model under which “genuine” or “convincing” smiling is a costly signal that has evolved to induce cooperation in situations requiring mutual trust. Prior to a trust interaction involving a decision by a sender to send money to a recipient, the recipient can emit a signal to induce the sender to trust them.
Centorrino, Samuele +4 more
openaire +5 more sources

