Quantitative Ultrasound Imaging and Artificial Intelligence in Neonatal Echocardiography: Methodological Advances, Reproducibility Challenges, and Computational Perspectives. [PDF]
Nikolaou AI +6 more
europepmc +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Applications of artificial intelligence in traditional Chinese medicine tongue diagnosis: a bibliometric review of research trends and hotspots, 2015-2026. [PDF]
Li Y +7 more
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Artificial Intelligence and Digital Technologies in Prakriti Assessment: Toward Standardized Evidence-Based Ayurvedic Practice. [PDF]
Allam R +4 more
europepmc +1 more source
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Fast robot-to-iOCT calibration using conical geometry and 2D cross-scan OCT. [PDF]
Gromada K +4 more
europepmc +1 more source
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
Vibrotactile stimulation for upper-limb neurorehabilitation and sensorimotor training: a systematic review of clinical and mechanistic evidence. [PDF]
Zhang W +7 more
europepmc +1 more source

