Results 111 to 120 of about 5,627,161 (307)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Two dimensional signal processing for storage channels [PDF]

open access: yes, 2016
Over the past decade, storage channels have undergone a steady increase in capacity. With the prediction of achieving 10 Tb/in2 areal density for magnetic recording channels in sight, the industry is pushing towards di erent technologies for storage ...
Soltanpur, Cinna
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Near-Field Localization and Sensing With Large-Aperture Arrays : From signal modeling to processing

open access: yes
The signal processing community is currently witnessing a growing interest in near-field signal processing, driven by the trend toward the use of large-aperture arrays with high spatial resolution in the fields of communication, localization, sensing ...
Ramezani, Parisa,   +7 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Fast algorithms for informed independent component/vector extraction

open access: yesEURASIP Journal on Advances in Signal Processing
We propose new and efficient algorithms for semi-blind source extraction derived from the well-known FastICA for independent component analysis (ICA). The algorithms assume independence of the source of interest (SOI) and other signals in the mixture and
Zbyněk Koldovský   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Spatiotemporal Hybrid Integration Algorithm for Airborne Target Detection and Localization in Multi-Illuminator GNSS-Based Passive Radar

open access: yesSensors
This paper addresses the fundamental power-budget limitation of global navigation satellite system (GNSS)-based passive radar in aircraft detection and localization by exploiting multiple satellite illuminators for spatiotemporal hybrid integration.
Fan Xu   +5 more
doaj   +1 more source

Warped wavelet bases: unitary equivalence and signal processing

open access: yes, 1993
Conference PaperThe notions of time, frequency, and scale are generalized using concepts from unitary operator theory and applied to time-frequency analysis, in particular the wavelet and short-time Fourier transform orthonormal bases and Cohen's class ...
Jones, Douglas L.   +3 more
core   +1 more source

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