Results 161 to 170 of about 5,627,161 (307)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Engineering microbial consortia for distributed signal processing. [PDF]

open access: yesNat Commun
Duncker KE   +11 more
europepmc   +1 more source

Sparse Blind Deconvolution Based On Scale Invariant Smoothed 0-norm

open access: yes, 2015
In this work, we explore the problem of blind deconvolution in the context of sparse signals. We show that the 0-norm works as a contrast function, if the length of the impulse response of the system is smaller than the shortest distance between two ...
Nose-Filho K., Romano J.M.T., Jutten C.
core  

Fractal Signal Processing

open access: yes
This paper presents a novel low-pass filtering framework based on Fractal First -order and Second -order designs, formulated within the framework of fractal calculus.
Şevli, Hamdullah   +4 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Speech Perception in Noise: A Narrative Review of Cognitive Contribution and Hearing-Aid Signal Processing. [PDF]

open access: yesJ Intell
Monzani D   +6 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

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