Rational Design of Inner Ear Drug Delivery Systems
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu+5 more
wiley +1 more source
Linear programming-based stabilization and synchronization of positive complex networks with dynamic link subsystems. [PDF]
Hong S+4 more
europepmc +1 more source
State of the Art of Low‐Frequency Acoustic Modulation: Intensity Enhancement and Directional Control
High intensity low‐frequency sound sources hold significant value in many fields. However, their long wavelength, strong penetrability, and tendency to diffract make direction control and intensity enhancement challenging. Acoustic generators and metamaterial‐based acoustic devices still face issues such as low energy efficiency, poor directional ...
Jingsong Xu+13 more
wiley +1 more source
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He+16 more
wiley +1 more source
Design and implementation of the dual-center programming platform for ternary optical computer and electronic computer. [PDF]
Zhang S+6 more
europepmc +1 more source
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang+4 more
wiley +1 more source
Building an open-source community to enhance autonomic nervous system signal analysis: DBDP-autonomic. [PDF]
Dunn J+7 more
europepmc +1 more source
CaLMPhosKAN: prediction of general phosphorylation sites in proteins via fusion of codon aware embeddings with amino acid aware embeddings and wavelet-based Kolmogorov-Arnold network. [PDF]
Pratyush P+5 more
europepmc +1 more source
Pilot Study on Using Large Language Models for Educational Resource Development in Japanese Radiological Technologist Exams. [PDF]
Kondo T, Okamoto M, Kondo Y.
europepmc +1 more source