Results 111 to 120 of about 3,600,645 (297)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

OFDM Signal Recovery in Deep Faded Erasure Channel

IEEE Access, 2019
In high-speed digital wireless communication applications, the intersymbol interference channel may have spectral nulls or erasures, which may degrade the orthogonal frequency division multiplexing (OFDM) bit error rate (BER) performance.
Alireza Rahmati, Kaamran Raahemifar, Theodoros A. Tsiftsis, Alagan Anpalagan, Paeiz Azmi   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Variational Bayesian Sparse Signal Recovery With LSM Prior

IEEE Access, 2017
This paper presents a new sparse signal recovery algorithm using variational Bayesian inference based on the Laplace approximation. The sparse signal is modeled as the Laplacian scale mixture (LSM) prior.
Shuanghui Zhang, Yongxiang Liu, Xiang Li, Guoan Bi   +3 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Research Into a Recovery Method of GNSS Authorized Service Signal Component

IEEE Access, 2018
A code recovery method of a global navigation satellite system (GNSS) authorized service (AS) signal component is described under the condition of a high signal-to-noise ratio. The correctness of the spreading code verification can be used to monitor the
Wei Xiao, Wenxiang Liu, Weihua Mou, Ling Yong, Guangfu Sun   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Nanoflowers Templated CuO/Cu Hybrid Metasurface for Sensitive THz‐TDS Detection of Acetylcholine

Advanced Sensor Research
Achieving sensitive detection using terahertz (THz) time‐domain spectroscopy (TDS) remains challenging due to the low probabilities of molecules being positioned within microscale active regions of typical THz metamaterials.
Soo Hyun Lee, Taeyeon Kim, Minah Seo
doaj   +1 more source

Signal Recovery from Randomly Quantized Data Using Neural Network Approach. [PDF]

Sensors (Basel), 2022
Al-Shaikhi A.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source