ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Toward ultracentrifugation-free processing and long-term preservation of outer membrane vesicles by culture optimization, tangential flow filtration, diafiltration, and lyophilization. [PDF]
Silva A +11 more
europepmc +1 more source
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source
Oxidative stress triggers RNAPII arrest through PARylation and DNA damage. [PDF]
Thomas QA +8 more
europepmc +1 more source
White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram +3 more
wiley +1 more source
Experimental Evaluation of GNSS Receiver Vulnerability to Spoofing and Jamming Using SDR-Based Testbed. [PDF]
Dułowicz J, Skokowski P, Kelner JM.
europepmc +1 more source
Endothelial Cell Proteins as Biomarkers in Susac Syndrome
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin +11 more
wiley +1 more source
Women's Health Wearables: From Continuous Signals to Actionable Digital Phenotypes Across the Reproductive Lifespan. [PDF]
AlSaad R +4 more
europepmc +1 more source
Streamlined stable CHO cell line development using droplet microfluidics with image-based monoclonality assessment. [PDF]
Naveen KV +4 more
europepmc +1 more source
Circuit-Level Transient Simulation Study of Recovery Characteristics in a Parallel-Resonator-Assisted GaN SBD Limiter. [PDF]
Zhao R +7 more
europepmc +1 more source

