Results 81 to 90 of about 3,652,766 (290)

Research on black-and-white imageprocessing method of smart car camera

open access: yesJournal of Measurement Science and Instrumentation, 2014
In view of the images collection and processing problems of the smart car camera,the paper introduces a method which deals with field and line synchronization signal separation and binarization processing of the video signal collected from track fields ...
LI Shi-guang   +3 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Contributions to theory and algorithms of independent component analysis and signal separation [PDF]

open access: yes, 2004
This thesis addresses the problem of blind signal separation (BSS) using independent component analysis (ICA). In blind signal separation, signals from multiple sources arrive simultaneously at a sensor array, so that each sensor array output contains a ...
Eriksson, Jan
core   +1 more source

Topology-based signal separation

open access: yesChaos: An Interdisciplinary Journal of Nonlinear Science, 2004
Traditional noise-filtering techniques are known to significantly alter features of chaotic data. In this paper, we present a noncausal topology-based filtering method for continuous-time dynamical systems that is effective in removing additive, uncorrelated noise from time-series data.
Robins, Vanessa   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The 2016 Signal Separation Evaluation Campaign [PDF]

open access: yes, 2017
International audienceIn this paper, we report the results of the 2016 community-based Signal Separation Evaluation Campaign (SiSEC 2016). This edition comprises four tasks.
Rivet, Bertrand   +15 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Spectro-temporal post-enhancement using MMSE estimation in NMF based single-channel source separation [PDF]

open access: yes, 2013
We propose to use minimum mean squared error (MMSE) estimates to enhance the signals that are separated by nonnegative matrix factorization (NMF). In single channel source separation (SCSS), NMF is used to train a set of basis vectors for each source ...
Erdoğan, Hakan   +3 more
core   +1 more source

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