Results 181 to 190 of about 559,864 (310)

Helmet-Head Decoupling in Ice Hockey Impacts: An In-lab Exploratory Study Using Autoregressive Modeling of Acceleration Data Measured from a Helmet-Mounted Inertial Measurement Unit (IMU). [PDF]

Ann Biomed Eng
Sciacca D, Ionescu A.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Research on self-adaptive height adjustment control of shearer based on deep deterministic policy gradient. [PDF]

PLoS One
Wang Y, Wang X, Lin G, Zhao L, Liu X, Jia B, Wang Y, He J, Ma L.   +8 more
europepmc   +1 more source

The effect of blood pressure calibrations and transcranial Doppler signal loss on transfer function estimates of cerebral autoregulation

, 2011
Brian Deegan, Jorge M. Serrador, Kazuma Nakagawa, Edward Jones, Farzaneh A. Sorond, Gearóid ÓLaighin   +5 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Electric-Field Quantum Sensing Exploiting a Photogenerated Charge-Transfer Triplet State in an Organic Molecule. [PDF]

J Am Chem Soc
Fontana N, Vaganov MV, Moise G, Myers WK, Peng K, Ardavan A, Liu J.   +6 more
europepmc   +1 more source

Impact of signal bandwidth and generic head-related transfer functions for localization on the horizontal plane in virtual acoustic space

, 1998
G. Robert Arrabito, R. B. Crabtree, Sharon McFadden, Sherry Van Blyderveen   +3 more
openalex   +1 more source

Proposal to perform transfer function measurements of the PARKA Critical Facility Reactor at LASL by cross-correlation with a pseudo-random input signal

, 1964
J.F. Hafer, Adam Wasserman, E.K. Honka
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source