Results 61 to 70 of about 559,864 (310)

Synthesis of transfer functions by signal-flow graphs

open access: yesElectronics Letters, 1974
A new procedure is given for the synthesis of voltage transfer functions. It is shown that the well known circuits of Lovering and Brugler can also be derived easily by this method. It is also indicated that a simplification can be obtained in the RC:-RC decomposition method. which is in the proposed procedure.
openaire   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Four-Channel Vibrating Testbed Design for Full Vehicle Durability Simulation

open access: yesJournal of Advanced Transportation, 2022
The four-channel vibrating testbed for full vehicle durability simulation is indispensable for testing vehicle performance. This paper combines theoretical analysis with experimental verification, and the four-channel vibrating simulation testbed is ...
Huiqi Du, Shiqing Xu
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research on Experimental Method for Obtaining Independent Combustion Noise of Internal Combustion Engine

open access: yesShock and Vibration, 2018
Internal combustion engine noise sources are complex and changeable. Combustion noise is usually drowned out by mechanical noise and aerodynamic noise. Traditional noise source identification methods can only qualitatively identify combustion noise.
Yang Xiang   +4 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Thermal noise limit for ultra-high vacuum noncontact atomic force microscopy

open access: yesBeilstein Journal of Nanotechnology, 2013
The noise of the frequency-shift signal Δf in noncontact atomic force microscopy (NC-AFM) consists of cantilever thermal noise, tip–surface-interaction noise and instrumental noise from the detection and signal processing systems.
Jannis Lübbe   +5 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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