Results 71 to 80 of about 541,244 (307)

Four-Channel Vibrating Testbed Design for Full Vehicle Durability Simulation

Journal of Advanced Transportation, 2022
The four-channel vibrating testbed for full vehicle durability simulation is indispensable for testing vehicle performance. This paper combines theoretical analysis with experimental verification, and the four-channel vibrating simulation testbed is ...
Huiqi Du, Shiqing Xu
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Thermal noise limit for ultra-high vacuum noncontact atomic force microscopy

Beilstein Journal of Nanotechnology, 2013
The noise of the frequency-shift signal Δf in noncontact atomic force microscopy (NC-AFM) consists of cantilever thermal noise, tip–surface-interaction noise and instrumental noise from the detection and signal processing systems.
Jannis Lübbe, Matthias Temmen, Sebastian Rode, Philipp Rahe, Angelika Kühnle, Michael Reichling   +5 more
doaj   +1 more source

New Equivalent Model of a Quantizer With Noisy Input and Its Applications for MIMO System Analysis and Design

IEEE Access, 2020
We propose a novel equivalent model for a quantizer with noisy input (the desired signal corrupted by measurement noise). It presents the quantizer output as a sum of the desired signal after it passes through a nonlinear element with a known equivalent ...
Arkady Molev-Shteiman, Xiao-Feng Qi, Laurence Mailander, Narayan Prasad, Bertrand M. Hochwald   +4 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

The foreground transfer function for H i intensity mapping signal reconstruction: MeerKLASS and precision cosmology applications [PDF]

, 2023
Steven Cunnington, Laura Wolz, Philip Bull, Isabella P. Carucci, Keith Grainge, Melis O Irfan, Yichao Li, Alkistis Pourtsidou, Mário G. Santos, Marta Spinelli, Jingying Wang   +10 more
openalex   +1 more source