Results 141 to 150 of about 108,709 (265)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Facial palsy reveals the sensorimotor contribution to facial-emotion recognition. [PDF]

Proc Natl Acad Sci U S A
Sessa P, Schiano Lomoriello A, Quettier T, Maffei A, Costa S, Nichele M, Ferrari PF.   +6 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Noise-Adversarial Denoising of Motor Acoustic Signals Across Noise Domains. [PDF]

Sensors (Basel)
Yang Y, Xu J, Jiang X, Xiao X, Dong H.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Cell surface ADGRG1 and CD86 expression identifies antitumor CD4⁺ T cells in human cancer. [PDF]

Proc Natl Acad Sci U S A
Hitscherich KJ, Dinerman AJ, Hakim AA, Dulemba V, Sindiri S, Gasmi B, Bera A, Gartner JJ, Prickett TD, Yu Z, Li YF, Ratnam NM, Gustafson AM, Bhasin A, Parkhurst MR, Klemen ND, Kwong MLM, Yang JC, Robbins PF, Goff SL, Rosenberg SA, Krishna S, Lowery FJ.   +22 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Cryo-EM structures of Cdr1 reveal snapshots of substrate transport and diverse inhibitor recognition. [PDF]

Sci Adv
Wang Z, Yang S, Zhang B, Jiang H, Li Y, Gao R, Wang Y, Fan F, Dong L, Qiu J, Li X, Zhou Y, Murchie AIH, Yu X.   +13 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Computable Phenotype for Identifying Undiagnosed Hypermobile Ehlers-Danlos Syndrome: Protocol for a Development and Validation Study. [PDF]

JMIR Res Protoc
Arvan M, Feinstein RT, Rudin NJ, Nichols M.   +3 more
europepmc   +1 more source