Results 181 to 190 of about 23,172 (222)

The neural pathways of change: an fMRI study of the effects of behavioral change suggestions on value-based dietary decision-making. [PDF]

open access: yesInt J Obes (Lond)
Rodrigues B   +11 more
europepmc   +1 more source

Multi-omics profiling identified two epithelioid sarcoma molecular subtypes with distinct signaling and immune characteristics. [PDF]

open access: yesCancer Commun (Lond)
Ngo C   +30 more
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Unbiased and comprehensive identification of virus-derived circular RNAs in a large range of viral species and families. [PDF]

open access: yesPLoS Pathog
Chasseur AS   +15 more
europepmc   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

open access: yesThe FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez   +7 more
wiley   +1 more source

Dual specificity phosphatase 1 as a non-invasive circulating biomarker candidate in preeclampsia. [PDF]

open access: yesFront Endocrinol (Lausanne)
Andrieu J   +8 more
europepmc   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

open access: yesThe FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas   +4 more
wiley   +1 more source

Uveal Melanoma and the Lynch Syndrome Tumor Spectrum.

open access: yesJAMA Ophthalmol
Le Ven A   +27 more
europepmc   +1 more source

Dual IRE1 targets: Determinants of the cell fate?

open access: yesThe FEBS Journal, EarlyView.
IRE1 is an ER stress sensor that restores protein homeostasis through two signaling activities: XBP1s, which upregulates its target gene expression or RIDD which downregulates its target transcripts. We recently identified Dual IRE1 Targets (DIT) which are modulated by both XBP1s and RIDD activities.
Eva Billat   +3 more
wiley   +1 more source

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