Results 81 to 90 of about 61,318 (225)

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Managing the Risk of IT Outsourcing [PDF]

While it can bring several benefits, IT outsourcing entails some risks. As it is the case in other types of investments or business ventures, the risk associated to an IT outsourcing project must be evaluated and managed.
Benoit A. Aubert, Michel Patry, Suzanne Rivard, Sylvie Dussault   +3 more
core  

Topological acceleration in relativistic cosmology

, 2012
Heuristic approaches in cosmology bypass more difficult calculations that would more strictly agree with the standard Einstein equation. These give us the well-known Friedmann-Lemaitre-Robertson-Walker (FLRW) models, and, more recently, the feedback ...
Roukema, Boudewijn F.
core   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

The non-segregated population of blue straggler stars in the remote globular cluster Palomar 14

, 2011
We used deep wide-field observations obtained with the Canada-France-Hawaii Telescope to study the blue straggler star (BSS) population in the innermost five arcminutes of the remote Galactic globular cluster Palomar 14.
Dalessandro, Dalessandro, Dotter, Ferraro, Ferraro, Ferraro, Ferraro, Ferraro, Hills, Jordi, Küpper, Lanzoni, Lanzoni, Mapelli, McCrea, Montegriffo, Preston, Sandquist, Shara, Sollima   +19 more
core   +3 more sources

Biocompatible Magnetopyroelectric Composite Films for Cell Stimulation

Advanced Science, EarlyView.
Magnetopyroelectric films couple Fe3O4 nanoparticles with pyroelectric P(VDF‐TrFE) to turn alternating magnetic fields into controlled heat and pyroelectric currents. This heavy‐metal free platform safely boosts neural progenitor cells differentiation via synergistic thermal and pyroelectrical cues, engages AKT and calcium pathways, and opens practical
Hao Ye, Joaquin Llacer‐Wintle, Semih Sevim, Elric Zhang, Denis von Arx, Lukas Hertle, Martina Accursi, Minsoo Kim, Josep Puigmartí‐Luis, Bradley J. Nelson, Xiang‐Zhong Chen, Salvador Pané   +11 more
wiley   +1 more source

Geoids in General Relativity: Geoid Quasilocal Frames

, 2015
We develop, in the context of general relativity, the notion of a geoid -- a surface of constant "gravitational potential". In particular, we show how this idea naturally emerges as a specific choice of a previously proposed, more general and ...
Epp, Richard J., Mann, Robert B., McGrath, Paul L., Oltean, Marius   +3 more
core   +3 more sources

Solution‐Shearing of Highly Smooth Ion‐Gel Thin Films: Facilitating the Deposition of Organic Semiconductors for Ion‐Gated Organic Field Effect Transistors

Advanced Electronic Materials, Volume 11, Issue 6, May 2025.
A straightforward method is introduced to produce ion‐gel films with very low surface roughness by employing a solution‐shearing coating process. These ion‐gel films permit the growth of crystalline thin films of various small molecule organic semiconductor molecules directly on top of the ion‐gel layer, thereby enabling “inverted” small molecule ...
Jonathan Perez Andrade, Angelika Wrzesińska‐Lashkova, Anupam Prasoon, Felix Talnack, Katherina Haase, Bernd Büchner, Xinliang Feng, Yana Vaynzof, Mike Hambsch, Yulia Krupskaya, Stefan C. B. Mannsfeld   +10 more
wiley   +1 more source

Bandgap‐Dependent Doping of Semiconducting Carbon Nanotube Networks by Proton‐Coupled Electron Transfer for Stable Thermoelectrics

Advanced Electronic Materials, EarlyView.
Proton‐coupled electron transfer doping with benzoquinone is applied to p‐dope dense films of semiconducting single‐walled carbon nanotubes. The doping efficiency depends on the pH of the doping solution and the bandgap of the nanotubes. The highest conductivities and power factors are achieved for small‐bandgap nanotubes, remaining stable for over 120
Angus Hawkey, Xabier Rodríguez‐Martínez, Sebastian Lindenthal, Moritz C. F. Jansen, Reverant Crispin, Jana Zaumseil   +5 more
wiley   +1 more source

Figures de la signature scientifique

, 2000
Studies of scientific collaboration based on publication have been developing for forty years. However, most of these studies are generally concentrated on productivity and the growth of ‘big science'. Involved with a sample of articles from three different fields, this work tries to reveal the patterns of publication at two levels : interdisciplinary,
openaire   +1 more source