Construction of anti-tumor immune gene signature for HNSCC and identification of 4'-Hydroxywogonin as a potential immunotherapy combination drug. [PDF]
Qiang W, Dai Y, Wang L, Wang J, Ge W.
europepmc +1 more source
Distributed Graph-based Topology Adaptation using Motif Signatures [PDF]
Michael Stein +7 more
openalex +1 more source
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source
Machine learning-driven dissection of the obesity-ccRCC interface: FCGR2A emerges as a central coordinator of tumor-immune crosstalk. [PDF]
He Z +7 more
europepmc +1 more source
This study establishes crucial genomic resources for adzuki bean, including a reference genome, variation map, and the AdzukiBeanAtlas toolkit. We identify key candidate genes (ANKRD50, NAC73, ANR1, NPF5.4) for important agronomic traits through Genome‐Wide Association Studies (GWAS).
Liangliang Hu +26 more
wiley +1 more source
Reconciling multiple connectivity-based systems biology methods for drug repurposing. [PDF]
Gonzalez Gomez C +2 more
europepmc +1 more source
ADNT: Discrete Number Topology and the Emergent Topological Signature of Prime Numbers (v1.0)
Dennis, Ceccaroli
openalex +2 more sources
Catalytic Electron‐Driven Non‐Equilibrium Phase Transition in Quantum Electronic Heterostructures
This study proposes an innovative method to control the phase of heterostructured materials via electron flow manipulation. Leveraging this technique, a new topological phase is achieved that hosts excitons at the interface of a topological insulator.
Byung Cheol Park +5 more
wiley +1 more source
Glypican-3 regulated epithelial mesenchymal transformation-related genes in osteosarcoma: based on comprehensive tumor microenvironment profiling. [PDF]
Zhang J, Wang W.
europepmc +1 more source

