Results 221 to 230 of about 676,033 (247)

A Ten-Gene Transcriptomic Biomarker Panel for Glioma Classification and Prognosis Identified via Integrative Hypergraph and Rough Set Analysis. [PDF]

Cancers (Basel)
Akgüller Ö, Balcı MA, Cioca G.
europepmc   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

A philosophical treatise on information, consciousness, and the architecture of perceived reality. [PDF]

Front Psychol
Martin PA.
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Graph informed biomarker discovery framework using transcriptomic machine learning for glioblastoma prognosis. [PDF]

Sci Rep
Mahmoud O, Mounir M, Gad W.
europepmc   +1 more source

Topological Data Analysis-Driven fNIRS Signal Processing for Alzheimer's Disease Stage Identification. [PDF]

Sensors (Basel)
Liu S, Wu H, Sun C, Qiu Y, Wu H, Wei Y, Lv Y, Yang Z.   +7 more
europepmc   +1 more source

A Topological and Spatial Analysis of FDA-Approved Drugs, Blood-Brain Barrier Permeants, Natural Products, and Metabolites. [PDF]

ChemMedChem
Masand VH, Al-Hussain SA, Quadri MSA, Samad A, Zaki MEA.   +4 more
europepmc   +1 more source

Identification and validation of oxidative stress-related immune signatures in Hepatitis B Virus associated acute liver failure based on WGCNA and machine learning. [PDF]

PLoS One
Dai L, Tan J, Zhou Z, Chen C, Hu G, Guo L.   +5 more
europepmc   +1 more source

Screening of Metabolic Reprogramming-Related Diagnostic Biomarkers and Analysis of Immune Heterogeneity in Atopic Dermatitis Based on Multi-Cohort Validation. [PDF]

Clin Cosmet Investig Dermatol
Zhi B, Song X.
europepmc   +1 more source

Spatiotemporal dynamics of scattering exceptional points. [PDF]

Nat Commun
Xiao Y, Che Z, Shi L, Wang X, Zhu J.
europepmc   +1 more source