Results 31 to 40 of about 8,568 (240)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A dichromatic polynomial for weighted graphs and link polynomials

, 1989
A dichromatic polynomial for weighted graphs is presented. The Kauffman bracket of a signed graph, an invariant inspired by the Jones polynomial of a link in three-space, is shown to be essentially an evaluation of this dichromatic polynomial, as are the
Lorenzo Traldi
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

GASP, a generalized framework for agglomerative clustering of signed graphs and its application to Instance Segmentation [PDF]

, 2022
We propose a theoretical framework that generalizes simple and fast algorithms for hierarchical agglomerative clustering to weighted graphs with both attractive and repulsive interactions between the nodes.
Kreshuk, Anna, Pape, Constantin, Beier, Thorsten, Bailoni, Alberto, Hamprecht, Fred A., Hütsch, Nathan, Wolf, Steffen   +6 more
core   +1 more source

Mathematical Modeling of Signed Graphs for Balancing Dynamic Systems

European Journal of Pure and Applied Mathematics
Signed graphs encode cooperative and antagonistic interactions in dynamical systems. In this paper we will study how explicit damping transforms unstable linearized dynamics into stable behavior, mapping the system Jacobian to a signed weighted matrix to
Abdulaziz Alotaibi, Khalid Al-Tahat, Khaled Mustafa Aljamal   +2 more
semanticscholar   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Task complexity shapes internal representations and robustness in neural networks

Machine Learning: Science and Technology
Neural networks excel across a wide range of tasks, yet remain ‘black boxes’. In particular, how their internal representations are shaped by the complexity of the input data and the problems they solve remains obscure. In this work, we introduce a suite
Robert Jankowski, Filippo Radicchi, M Ángeles Serrano, Marián Boguñá, Santo Fortunato   +4 more
doaj   +1 more source

Bounds for the energy of weighted graphs

Discrete Applied Mathematics, 2019
Let G be a simple connected graph with n vertices and m edges. Let W ( G ) = ( G , w ) be the weighted graph corresponding to G . Let λ 1 , λ 2 , … , λ n be the eigenvalues of the adjacency matrix A ( W ( G ) ) of the weighted graph W ( G ) .
Hilal A. Ganie, Bilal A. Chat
semanticscholar   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source