Results 121 to 130 of about 2,598,126 (331)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

An algorithmic approach to signed fuzzy graph integrity: Complexity, graph operations, and metro rail network applications

open access: yesAin Shams Engineering Journal
This paper presents an algorithm to compute the integrity of a signed fuzzy graph by systematically evaluating vertex subsets, removing them, and analyzing the resulting connected components.
Chakaravarthy Sankar   +3 more
doaj  

Edges and vertices in a unique signed circle in a signed graph

open access: yesAKCE International Journal of Graphs and Combinatorics, 2017
We examine the conditions under which a signed graph contains an edge or a vertex that is contained in a unique negative circle or a unique positive circle.
Richard Behr
doaj   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao   +4 more
wiley   +1 more source

Whole-Graph Representation Learning for the Classification of Signed Networks

open access: yesIEEE Access
Graphs are ubiquitous for modeling complex systems involving structured data and relationships. Consequently, graph representation learning, which aims to automatically learn low-dimensional representations of graphs, has drawn a lot of attention in ...
Noe Cecillon   +3 more
doaj   +1 more source

Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller   +12 more
wiley   +1 more source

On signed degrees in signed graphs [PDF]

open access: yesCzechoslovak Mathematical Journal, 1994
Gary Chartrand   +3 more
openaire   +2 more sources

Plasma microRNA Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone   +19 more
wiley   +1 more source

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