Graph neural networks in the nephropathological diagnosis of antibody-mediated rejection. [PDF]
Mateos-Aparicio-Ruiz I +4 more
europepmc +1 more source
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan +9 more
wiley +1 more source
SPICEiST: subcellular RNA pattern enhances cell clustering of imaging-based spatial transcriptomics. [PDF]
Bae S, Seong Y, Lee D, Choi H.
europepmc +1 more source
Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
Graph models of brain state in deep anesthesia reveal sink state dynamics of reduced spatiotemporal complexity. [PDF]
Wilsenach JB +3 more
europepmc +1 more source
Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay +3 more
wiley +1 more source
Steering polarization toward consensus in signed majority-vote opinion models. [PDF]
Chujyo M, Liu S, Toriumi F.
europepmc +1 more source
A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova +7 more
wiley +1 more source
Effects of Autologous Blood-Derived Extracellular Vesicles on Skin Regeneration and Anti-Aging: A Clinical Study. [PDF]
Kang H +6 more
europepmc +1 more source
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney +3 more
wiley +1 more source

