Results 251 to 260 of about 329,714 (296)

Potential eventual positivity of sign patterns with the underlying broom graph

open access: hybrid, 2016
Ber-Lin Yu   +3 more
openalex   +1 more source

Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC‐Derived Liver Progenitor Cell Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain   +5 more
wiley   +1 more source

Mature dengue virus particles inactivated by a non-ionic detergent retain quaternary neutralizing epitopes and induce potent neutralizing antibodies. [PDF]

open access: yesFront Immunol
Tsai WY   +8 more
europepmc   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark   +9 more
wiley   +1 more source

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

open access: yesAdvanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty   +5 more
wiley   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel   +13 more
wiley   +1 more source

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