Results 41 to 50 of about 928,791 (254)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Characterization of Line-Consistent Signed Graphs
Discussiones Mathematicae Graph Theory, 2015 The line graph of a graph with signed edges carries vertex signs. A vertex-signed graph is consistent if every circle (cycle, circuit) has positive vertex-sign product. Acharya, Acharya, and Sinha recently characterized line-consistent signed graphs, i.e.
Slilaty Daniel C., Zaslavsky Thomas
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On balanced cycle domination of graphs
AKCE International Journal of Graphs and Combinatorics, 2023 Let [Formula: see text] be a graph. A function [Formula: see text] is said to be a balanced cycle dominating function (BCDF) of [Formula: see text] if [Formula: see text] holds for any induced cycle [Formula: see text] of [Formula: see text] The balanced
Baogen Xu +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
On colorings and orientations of signed graphs [PDF]
Discrete Mathematics Letters, 2023 Daniel Slilaty
doaj +1 more source
Computation of the eigenvalues of complete signed graphs
Electronic Journal of Graph Theory and ApplicationsA signed graph Σ is the ordered pair (G,σ), where G=(V,E) is a finite simple graph, called the underlying graph, and σ: E(G) → {+1, -1} is a sign function or a signature of Σ. Let (K_n,σ) be a complete signed graph with n vertices. In this paper, we give
Shariefuddin Pirzada +3 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
On the signed Italian domination of graphs [PDF]
Computer Science Journal of Moldova, 2019 A signed Italian dominating function on a graph $G=(V,E)$ is a function $f:V\to \{ -1, 1, 2 \}$ satisfying the condition that for every vertex $u$, $f[u]\ge 1$. The weight of signed Italian dominating function is the value $f(V)=\sum_{u\in V}f(u)$.
Ashraf Karamzadeh +2 more
doaj