Results 161 to 170 of about 37,702 (263)

Tuft cell cysteinyl leukotrienes are necessary for rhinovirus-induced mucus metaplasia, type 2 inflammation and airway hyperresponsiveness in immature mice. [PDF]

Front Immunol
Parker DT, Bentley JK, Lei J, Domala B, Briggs HL, Singh S, Li Y, Reiner MC, Flores DA, Sliwicki AL, Flori HR, Hershenson MB.   +11 more
europepmc   +1 more source

Variable-Signed Graph

Variable-Signed Graph
application/pdf Bulletin of University of Osaka Prefecture. Series A, Engineering and natural sciences.
openaire  

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Beta Integrin Expression Defines Functionally Distinct CD4⁺ T-Cell Subsets That Are Altered in Ulcerative Colitis. [PDF]

Gastro Hep Adv
Ward-Hartstonge KA, Ivison S, Huang Q, Cook L, Bressler B, Levings MK, Gastrointestinal Research Institute Study Group.   +6 more
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

TGF-β-driven NK Cells plasticity in hepatocellular carcinoma. [PDF]

Front Immunol
Reverberi V, Montali A, Vecchi A, Rossi M, Pelagatti A, Doselli S, Farina B, Olivani A, Economopoulos G, Dalla Valle R, Laccabue D, Ferraglia F, Penna A, Fisicaro P, Boni C, Missale G.   +15 more
europepmc   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Longitudinal profiling of serum ADAM17 across clinical stages in multiple myeloma: a dynamic biomarker and its association with T cell alterations. [PDF]

Front Mol Biosci
Qu J, Li Y, Li C, Wu D, Cao Y, Xiao S, Bao X, Li Q, Chen Z, Chen L.   +9 more
europepmc   +1 more source

Nanobiosensor Based on Catalytic Palladium Nanoclusters and Oxidases for Bianalyte Electrochemical Determination: Glucose and Ethanol in Sweat

Advanced Healthcare Materials, EarlyView.
A nanobiosensor for fast and simultaneous determination of sweat glucose and ethanol is presented. Deposited oxidase enzymes consume oxygen in the presence of the substrates, and co‐deposited palladium nanoclusters catalyze the electrochemical oxygen reduction, basis of the detection.
Alejandro Rodríguez‐Penedo, Estefanía Costa‐Rama, Beatriz Fernández, M. Teresa Fernández‐Abedul   +3 more
wiley   +1 more source

Uni-hemispheric dual-site anodal tDCS (M1-DLPFC) for upper limb motor function and spasticity in chronic stroke: a randomized clinical trial. [PDF]

Front Neurol
Ezzati K, Naghdi S, Abdollahi I, Azarnia S, Jaberzade S.   +4 more
europepmc   +1 more source