Results 51 to 60 of about 295,176 (285)
Open Journal of Occupational Therapy, 2022 Background: Informal caregivers are susceptible to compassion fatigue in vicarious response to another’s suffering. The purpose of the study was to determine the feasibility of an online program that addresses compassion fatigue, burnout, and secondary ...
Emily C. Koller +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Nonlocal balance equations with parameters in the space of signed measures
, 2022 A parametric family of nonlocal balance equations in the space of signed measures is studied. Under assumptions that cover a number of known conceptual models we establish the existence of the solution, its uniqueness and continuous dependence on the ...
Pogodaev, NI, Staritsyn, MV
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A política de inovação e a formação do químico
Química Nova, 2013 In December 2004, Brazil's President signed Law number 10.973, which provides for incentives toward innovation, scientific and technological research in the production environment and other measures, also known as the Law of Innovation.
Sérgio de Paula Machado
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Recunoaşterea Unirii Basarabiei cu România – aspecte istorice şi de drept internaţional [PDF]
Polis: Revista de Stiinte Politice, 2018 This paper deals with the recogniton of Sfatul Ţării act of 27 March 1918 - the legal basis of the Bessarabia union with Romania - in international law, by the states who signed the 1920 Peace Treaty of Paris and by the Soviet Russia/Soviet Union.
Radu CARP
doaj
Bayesian AnalysisPoint processes and, more generally, random measures are ubiquitous in modern statistics. However, they can only take positive values, which is a severe limitation in many situations. In this work, we introduce and study random signed measures, also known as real-valued random measures, and apply them to constrcut various Bayesian non-parametric models.
openaire +2 more sources