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Statistical Significance Versus Clinical Significance

Seminars in Cardiothoracic and Vascular Anesthesia, 2008
Unfortunately, the data were statistically nonsignificant due to insufficient power and poor experimental design. Conversely, many large clinical trials obtain a high level of statistical significance with miniscule differences between groups, which are completely clinically irrelevant. However, with proper marketing, billions can be made from results
Timothy T, Houle, David A, Stump
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The significance of 'no significant difference'

Acta Radiologica, 1990
It is generally accepted that patients experience less discomfort with low osmolality contrast media (LOM) than with high osmolar media (HOM). Hard statistical facts from so called ‘high quality’ controlled trials, proving that more significant reactions such as vomiting, hives, urticaria or anaphylactic complications also are less common with LOM are,
J, Brismar, B, Jacobsson
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Is Statistical Significance Always Significant?

Nutrition in Clinical Practice, 2005
One way in which we learn new information is to read the medical literature. Whether or not we do primary research, it is important to be able to read literature in a critical fashion. A seemingly simple concept in reading is to interpret p values. For most of us, if we find a p value that is <.05, we take the conclusion to heart and quote it at ...
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The significance of statistical significance

Intensive and Critical Care Nursing, 1997
Currently, much nursing practice is based on limited evidence, for example, small-scale research, case studies and clinical experience. In a mature science this would be undesirable, but nursing is in the early stages of development as a science, and many of its practices depend on relatively informal knowledge.
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Significance tests

British Dental Journal, 1989
Simple methods of determining whether the difference between a sample mean and a given standard value is likely to be due only to sampling error, or to be real and/or of practical importance, are described. The use of the null hypothesis and of standard normal deviates is discussed, and examples are provided to illustrate the points made.
J S, Bulman, J F, Osborn
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Significant or Not Significant

Research Quarterly. American Association for Health, Physical Education and Recreation, 1963
(1963). Significant or Not Significant. Research Quarterly. American Association for Health, Physical Education and Recreation: Vol. 34, No. 2, pp. 239-242.
Dale O. Nelson, Rex L. Hurst
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Signifying significant significance.

American Psychologist, 1972
Jerold D. Bozarth, Ralph R. Roberts
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Significance, non-significance — who has found significance?

Pain, 1993
Mark A, Slater   +2 more
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