Results 101 to 110 of about 33,233,550 (381)

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Identification of foxtail millet (Seteria italica (L.) P. Beauv.) genotypes for multi-season adaptability using GGE biplot analysis in Foothills of Nagaland

open access: yesElectronic Journal of Plant Breeding
Foxtail millet is a main millets crop of Northeastern region of India. The genotype-by-environment analyses assist in understanding the potential performance of the genotypes over environments.
D. Purushotama Rao1 and H. P Chaturvedi2*
doaj   +1 more source

Relationship between problem-based learning experience and self-directed learning readiness [PDF]

open access: yes, 2007
Tun Hussein Onn University of Malaysia (UTHM) has been implementing Problem-Based Learning (PBL) to some degree in various subjects. However, to this day no empirical data has been gathered on the effectiveness of PBL as a methodology to develop self ...
Zainal Alam, Siti Nurzakiah
core  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

The significance of 'Blastocystis' in different hosts [PDF]

open access: yes, 2012
Blastocystis is an obligate anaerobic, protistan parasite found in the intestinal tract of human\ud and various other hosts. Blastocystis is placed within the stramenopiles. This diverse group\ud also includes slime nets, water moulds and brown algae.
openaire   +2 more sources

Spontaneous photon emission stimulated by two Bose condensates

open access: yes, 1996
We show that the phase difference of two overlapping ground state Bose-Einstein condensates can effect the optical spontaneous emission rate of excited atoms.
Ruostekoski, Janne   +2 more
core   +2 more sources

Pilot investigation of a virtual gastric band hypnotherapy intervention [PDF]

open access: yes, 2016
This was a pilot investigation of 30 men and women with a BMI > 27kg/m² over a 24 week period. It aimed to determine whether virtual gastric band (VGB) hypnotherapy has an effect on weight loss in overweight adults, compared to relaxation hypnotherapy ...
Atkin, Stephen   +8 more
core   +1 more source

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