Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Assessing the Minimally Clinically Significant Difference: Scientific Considerations, Challenges and Solutions [PDF]
, 2005 Jeff A. Sloan
openalex +1 more source
COUNTY LEVEL TAXABLE AGRICULTURAL LAND VALUES IN NORTH DAKOTA: COMPARING THE GROSS REVENUE APPROACH WITH VALUES BASED ON RENTAL VALUES [PDF]
Land values calculated with the current North Dakota agricultural land valuation model were compared with values calculated by capitalizing the average cash rent for each county.
Aakre, Dwight G., Haugen, Ronald H.
core +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Significant differences in nucleocapsid morphology within the Paramyxoviridae
, 2002 David Bhella +3 more
openalex +1 more source
Significant Morphological but Little Molecular Differences Between Trypanosoma of Rodents From Alaska [PDF]
, 2005 Juha Laakkonen +4 more
openalex +1 more source
Comparison of Prevalence and Number of Lentigo, Freckle, Melanocytic Nevus and other Neavus Lesions in Women with and without Melasma [PDF]
Introduction: Melasma is applied to a pattern of pigmentation seen mainly in women, and may be regarded as a physiological change in pregnancy. the hypermelanosis affects the upper lip, cheeks, forehead and chin and becomes more apparent following sun ...
امینی ثانی, نیره +2 more
core
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source