Results 51 to 60 of about 4,590 (273)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Trends in Hearing, 2023 Speech that has been artificially accelerated through time compression produces a notable deficit in recall of the speech content. This is especially so for adults with cochlear implants (CI).
Ryan M. O’Leary +6 more
doaj +1 more source
Functional timing or rhythmical timing, or both? A corpus study of English and Mandarin duration
Frontiers in Psychology, 2023 It has been long held that languages of the world are divided into rhythm classes so that they are either stress-timed, syllable-timed or mora-timed. It is also known for a long time that duration serves various informational functions in speech.
Chengxia Wang, Yi Xu, Jinsong Zhang
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Comparison of silent pauses in Japanese synthesized and natural speech
, 2023 The current study attempts to investigate differences of silent pauses in natural and Siri's synthesized speech in Japanese, and the perceptual effects of pause lengths on native speakers.
Chiaki Sweet
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Blocking of word-boundary consonant lengthening in Sienese Italian [PDF]
, 2006 This paper examines an aspect of Raddoppiamento sintattico (RS), the lengthening of word-initial consonants following certain words e.g. tre [mm]ele ‘three apples’ in Italian. Most phonological accounts claim the phenomenon is predictable and obligatory (
Warren, Paul +3 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Turn Taking in Mata Najwa Talk Show "Ragu-Ragu Perpu" Episode: A Conversational Analysis
Journal of Pragmatics Research, 2020 The present research aims to investigate the key features of turn taking in Mata Najwa talk show about Ragu-ragu Perpu (doubtful of rules of law). In addition, the authors propose to describe the use of turn-taking features between speaker to listener in
Firdaus Habibi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source