Results 71 to 80 of about 75,189 (260)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

Stabilized Bi(III) Sites Direct *NH2OH Pathway for Efficient Cyclohexanone Oxime Electrosynthesis

Advanced Materials, EarlyView.
The electron‐buffering effect stabilizes Bi3+ sites under electroreductive conditions, preserving a favorable interfacial water configuration that sustains the selective *NH2OH pathway and enables efficient cyclohexanone oxime electrosynthesis. ABSTRACT Coupling electrocatalytic nitrite reduction reaction (NO2−RR) with cyclohexanone conversion enables ...
Zichao Xi, Yan Du, Haijing Li, Jian Shang, Jinxiao Wu, Peng Li, Huimin Yu, Tianyi Ma, Huanyu Jin   +8 more
wiley   +1 more source

A comparative study of non-covalent encapsulation methods for organic dyes into silica nanoparticles

Nanoscale Research Letters, 2011
Numerous luminophores may be encapsulated into silica nanoparticles (< 100 nm) using the reverse microemulsion process. Nevertheless, the behaviour and effect of such luminescent molecules appear to have been much less studied and may possibly prevent
Auger Aurélien, Samuel Jorice, Poncelet Olivier, Raccurt Olivier   +3 more
doaj  

RETRACTED: Reactive Mesoporous pH-Sensitive Amino-Functionalized Silica Nanoparticles for Efficient Removal of Coomassie Blue Dye

Nanomaterials, 2019
In this work, new smart mesoporous amine-functionalized silica nanoparticles were prepared from hydrolyzing microgels based on N-isopropyl acrylamide-co-vinyltrimethoxysilane microgels with tetraethoxysilicate and 3-aminopropyltriethoxysilane by sol-gel ...
Nourah I. Sabeela, Tahani M. Almutairi, Hamad A. Al-Lohedan, Abdelrahman O. Ezzat, Ayman M. Atta   +4 more
doaj   +1 more source

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

Advanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source

Subcellular Distribution and Genotoxicity of Silica Nanoparticles 
in Human Bronchial Epithelial Cells

Chinese Journal of Lung Cancer, 2013
Background and objective Silicon nanoparticles are widely used in daily life. Therefore, they attract increased attention because of their potential biotoxicity to the lungs when inhaled.
Guangqiang ZHAO, Yunchao HUANG, Guangjian LI, Sen LI, Yongchun ZHOU, Yujie LEI, Xiaobo CHEN, Kaiyun YANG, Ying CHEN, Kun YANG   +9 more
doaj   +1 more source

Canine mesenchymal stem cells are effectively labeled with silica nanoparticles and unambiguously visualized in highly autofluorescent tissues

BMC Veterinary Research, 2012
Background Development of a method for long-term labeling of cells is critical to elucidate transplanted cell fate and migration as well as the contribution to tissue regeneration.
Han Sei-Myoung, Lee Hee-Woo, Bhang Dong-Ha, Seo Kyoung-Won, Youn Hwa-Young   +4 more
doaj   +1 more source

Hybrid Amyloid–Boron Nitride Aerogels for Lightweight Sound Insulation

Advanced Materials, EarlyView.
Amyloid fibrils template the mild formation of boron nitride–rich hybrid aerogels with hierarchical porosity, enhanced BN‐like ordering, and fibril‐reinforced mechanics. These ultralight materials combine thermal stability with strong sound absorption and transmission loss, offering a sustainable bio‐assisted route toward lightweight acoustic shields ...
Mohammad Peydayesh, Andrin Lustgarten, Stefan Schoenwald, Enrico Boschi, My Hanh Bui, Ali Miserez, Felix Donat, Christoph R. Müller, Raffaele Mezzenga   +8 more
wiley   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source