Results 41 to 50 of about 777,550 (307)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

LXII.—Silver dioxide and silver peroxynitrate [PDF]

J. Chem. Soc., Trans., 1906
n ...
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

TALA SILVER SPEAK SILVER

, 2023
From the publisher: Tala Silver (Speak Silver), published in conjunction with Nutida Svenskt Silver’s 60th anniversary, gives us a glimpse of the member smiths’ practices, and places contemporary artistic silver and goldsmithing in a wider social ...
Ljungberg, Anders, Silfverstolpe, Sofia, Cilla Robach, Cilla, Birgersson, Tobias,, Wickman, Kerstin   +4 more
core  

Inactivation of the antibacterial and cytotoxic properties of silver ions by biologically relevant compounds [PDF]

, 2014
There has been a recent surge in the use of silver as an antimicrobial agent in a wide range of domestic and clinical products, intended to prevent or treat bacterial infections and reduce bacterial colonization of surfaces. It has been reported that the
Jenkins A. Tobias A., Mulley, Geraldine, Geraldine Mulley, Waterfield, Nicholas R., A Tobias A Jenkins, Jenkins, A. Tobias A., Nicholas R Waterfield, Mulley Geraldine, Waterfield Nicholas R.   +8 more
core   +2 more sources

Reported asthma and dental amalgam exposure among adults in the United States: An assessment of the National Health and Nutrition Examination Survey

SAGE Open Medicine, 2021
Objective: Mercury (Hg)-based amalgam is a dental restorative material in common use. This hypothesis-testing study evaluated the relationship between dental amalgam exposure and the risk of reported asthma diagnoses in American adults.
David A Geier, Mark R Geier
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The Politics of Regulation: Adolescent Mothers and the Social Context of Resiliency

, 2008
The experiences of adolescent mothers have too often been reduced to patterns of correlation linking teenage parenthood with low educational attainment, persistent poverty and continued welfare dependency. These analyses have reinforced representation of
Silver, Lauren J.
core   +1 more source

Where, What, When, and Why Is Bottom Mapping Needed? An On-Line Application to Set Priorities Using Expert Opinion

Geosciences, 2018
Globally, there is a lack of resources to survey the vast seafloor areas in need of basic mapping data. Consequently, smaller areas must be prioritized to address the most urgent needs.
Matthew S. Kendall, Ken Buja, Charles Menza, Tim Battista   +3 more
doaj   +1 more source