Results 41 to 50 of about 876,281 (315)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Case review and imaging: Treatment of central venous catheter associated fibrin sheath and chronic thrombus with the ClotTriever system

Radiology Case Reports
Fibrin sheath formation is a leading culprit of central venous catheter malfunction. The complete removal of fibrin sheaths is an essential component of maintaining catheter patency, preventing future restenosis, and decreasing the risk of bloodborne ...
Kamil Tomaszek, RN, BSN, Feraz Rahman, MD, MS   +1 more
doaj   +1 more source

Cell-Mediated Immunity Generated in Response to a Purified Inactivated Vaccine for Dengue Virus Type 1

mSphere, 2020
Dengue is the most prevalent arboviral disease afflicting humans, and a vaccine appears to be the most rational means of control. Dengue vaccine development is in a critical phase, with the first vaccine licensed in some countries where dengue is endemic
Heather Friberg, Luis J. Martinez, Leyi Lin, Jason M. Blaylock, Rafael A. De La Barrera, Alan L. Rothman, J. Robert Putnak, Kenneth H. Eckels, Stephen J. Thomas, Richard G. Jarman, Jeffrey R. Currier   +10 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Bactericidal and Cytotoxic Properties of Silver Nanoparticles

International Journal of Molecular Sciences, 2019
Silver nanoparticles (AgNPs) can be synthesized from a variety of techniques including physical, chemical and biological routes. They have been widely used as nanomaterials for manufacturing cosmetic and healthcare products, antimicrobial textiles, wound
C. Liao, Yuchao Li, S. Tjong
semanticscholar   +1 more source

Bactericidal activity of silver nanoparticles: A mechanistic review

Materials Science for Energy Technologies, 2020
Metallic nanoparticles such as silver nanoparticles (AgNPs) have gained lots of attention due to the continuous upsurge in microbial infections and diseases, and also inefficient treatment.
Syed Anees Ahmad, S. S. Das, A. Khatoon, M. Ansari, M. Afzal, Saquib Hasnain, A. Nayak   +6 more
semanticscholar   +1 more source

Where, What, When, and Why Is Bottom Mapping Needed? An On-Line Application to Set Priorities Using Expert Opinion

Geosciences, 2018
Globally, there is a lack of resources to survey the vast seafloor areas in need of basic mapping data. Consequently, smaller areas must be prioritized to address the most urgent needs.
Matthew S. Kendall, Ken Buja, Charles Menza, Tim Battista   +3 more
doaj   +1 more source

LXII.—Silver dioxide and silver peroxynitrate [PDF]

J. Chem. Soc., Trans., 1906
n ...
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Mechanistic Basis of Antimicrobial Actions of Silver Nanoparticles

Frontiers in Microbiology, 2016
Multidrug resistance of the pathogenic microorganisms to the antimicrobial drugs has become a major impediment toward successful diagnosis and management of infectious diseases.
T. C. Dakal, Anu Kumar, R. Majumdar, Vinod Yadav   +3 more
semanticscholar   +1 more source