Anti-proliferative potential of phytochemical fractions isolated from Simarouba glauca DC leaf [PDF]
Heliyon, 2020 Emerging advancements in anticancer drug discovery research are leaning towards the plant-based bioactive fractions, which is a cocktail of naturally abundant two or more substances with unique proportions, exhibiting greater potential to combat cancers ...
SubbaRao V Madhunapantula +2 more
exaly +4 more sources
Oral acute and sub-chronic toxicity assessment of aqueous leaf extract of Simarouba glauca DC (Paradise tree) [PDF]
Toxicology Reports, 2021 Simarouba glauca has been widely reported to be effective against a number of diseases and possesses medicinal benefits. Thus, the study was conducted to evaluate the toxic effect of aqueous leaf extract of Simarouba glauca (AESG) on relevant organs of ...
SD. E. Osagie-Eweka +3 more
doaj +2 more sources
Broad-Spectrum Antimicrobial, Antioxidant, and Anticancer Studies of Leaf Extract of Simarouba glauca DC In Vitro [PDF]
Antibiotics, 2022 The current study aimed to screen the preliminary phytochemicals in the leaf extract of the medicinal plant Simarouba glauca and to analyze its potential antimicrobial, antioxidant and anticancer properties.
Shanmuga Priya Ramasamy +11 more
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Molecular identification of sex in Simarouba glauca by RAPD markers for crop improvement strategies [PDF]
Biotechnology Reports, 2014 Due to lack of morphological methods to identify sex at early stage in the plants with long juvenile period the application of molecular markers is expected to facilitate breeding program.
Gayatri Vaidya, G.R. Naik
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Alpha glucosidase inhibition activity of phenolic fraction from Simarouba glauca: An in-vitro, in-silico and kinetic study [PDF]
Heliyon, 2020 A phenolic rich fraction purified from Simarouba glauca leaves was effective in alpha glucosidase inhibition. The purified fraction named ‘fraction-14’ had shown significant inhibition of yeast alpha glucosidase enzyme activity (IC50 = 2.4 ± 0.4 μg/mL ...
Kirana P. Mugaranja, Ananda Kulal
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Green synthesis of Simarouba glauca seed-mediated silver nanoparticles: physicochemical characterization and cytotoxic mechanisms in HepG2 hepatocellular carcinoma cells [PDF]
Discover NanoThis study aims to synthesize Simarouba glauca seed-mediated silver nanoparticles (Sg-AgNPs) through an eco-friendly approach and to evaluate their antioxidant, anti-inflammatory, and anticancer efficacy against HepG2 hepatocellular carcinoma cells.
V. Mariya Angel Augasta +9 more
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Bioactivity-Guided Fractionation, Characterization, and Mechanistic Insights of Anticancer Agents from Simarouba glauca DC. Leaves [PDF]
MoleculesAlthough Simarouba glauca DC. has been recognized for its therapeutic properties, its anticancer effects against oral cancer have not been adequately investigated. The present study aimed to evaluate the activity of S.
Sushma Rudraswamy +4 more
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Chloroplast genomes of Simarouba Aubl., molecular evolution and comparative analyses within Sapindales [PDF]
Scientific ReportsSimarouba, a neotropical genus in the family Simaroubaceae, currently lacks comprehensive genomic data in existing databases. This study aims to fill this gap by providing genomic resources for three Simarouba species, S. amara, S.
Marla A. Almeida-Silva +8 more
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In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Dengue and chikungunya are two important mosquito-borne infections which are known to occur extensively in tropical and subtropical areas. Presently, there is no treatment for these viral diseases.
Kalichamy Alagarasu +9 more
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Tricaproin Isolated From Simarouba glauca Inhibits the Growth of Human Colorectal Carcinoma Cell Lines by Targeting Class-1 Histone Deacetylases [PDF]
Frontiers in Pharmacology, 2018 While anticancer properties of Simarouba glauca (SG, commonly known as Paradise tree) are well documented in ancient literature, the underlying mechanisms leading to cancer cell death begin to emerge very recently.
Asha Jose +3 more
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