Results 151 to 160 of about 1,581,512 (316)
Do Similar Entities Have Similar Embeddings?
Knowledge graph embedding models (KGEMs) developed for link prediction learn vector representations for entities in a knowledge graph, known as embeddings. A common tacit assumption is the KGE entity similarity assumption, which states that these KGEMs retain the graph's structure within their embedding space, \textit{i.e.}, position similar entities ...
Nicolas Hubert +3 more
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Similarity-based cognition: radical enactivism meets cognitive neuroscience
, 2019 2019, Springer Nature B.V. Similarity-based cognition is commonplace. It occurs whenever an agent or system exploits the similarities that hold between two or more items-e.g., events, processes, objects, and so on-in order to perform some cognitive task.
Daniel Hutto (19584613) +1 more
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Does Auditory Similarity Affect the Usefulness of Cues to Perceived Relative Distance?
, 2005 This study investigated the effects of auditory similarity on cues to relative distance. Vision literature has suggested that some common visual illusions involving size contrast depend on certain physical or conceptual characteristics of the objects ...
Chipley, Michael Ryan
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
<h2><a href="https://github.com/mljs/tree-similarity/compare/v1.0.0...v2.0.0">2.0.0</a> (2024-02-08)</h2> <h3>⚠ BREAKING CHANGES</h3> <ul> <li>treeSimilarity now only accepts Tree objects</li> <li ...
Michaël Zasso +4 more
core +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Italy and China Agri-Food Trade: Integration, Similarity and Competition
The paper looks at the increasing integration of China into the world market, with a specific focus on agricultural and food trade and on the Italian market.
Antimiani, Alessandro, Henke, Roberto
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source