PySimi: a unified framework for similarity measure evaluation in spectral clustering with applications to omics data. [PDF]
Front GenetShi T, Ye X, Zou Z, Xi W, Sakurai T.
europepmc +1 more source
Appropriate Similarity Measures for Author Cocitation Analysis [PDF]
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory ...
Waltman, L.R., Eck, N.J.P. van
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
KGTC-DDA:Drug-disease association prediction based on parallel graph isomorphism and transformer networks with cross-attention. [PDF]
Biochem Biophys RepChen J +5 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
What Provider Frequently Asked Questions Miss: Evaluating Unmet Attention-Deficit/Hyperactivity Disorder Information Needs Through Comparison of Online Community Posts Using Large Language Model-Assisted Semantic Analysis in a Mixed Methods Study. [PDF]
J Med Internet ResBaek J, Kim H.
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Does Auditory Similarity Affect the Usefulness of Cues to Perceived Relative Distance?
, 2005 This study investigated the effects of auditory similarity on cues to relative distance. Vision literature has suggested that some common visual illusions involving size contrast depend on certain physical or conceptual characteristics of the objects ...
Chipley, Michael Ryan
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
PyCompound: An Open-Source Python Package for Spectral-Library Matching in Mass Spectrometry-Based Metabolomics. [PDF]
MetabolitesDlugas H +5 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source