Results 111 to 120 of about 21,703 (289)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Belt and road initiative membership and voting patterns in the United Nations General Assembly

open access: yesResearch & Politics
The Belt and Road Initiative (BRI) is not only an unprecedented cross-continental infrastructure investment program, it is also a key pillar of China’s foreign policy.
Christoph V Steinert, David Weyrauch
doaj   +1 more source

Overseas GP recruitment: comparing international GP training with the UK and ensuring that registration standards and patient safety are maintained

open access: yesBJGP Open, 2019
Background: Ambitious overseas recruitment targets have been set by the UK government to help alleviate the current GP shortage. European Economic Area (EEA) doctors can join the UK’s GP register under European law.
Emily Fletcher   +6 more
doaj   +1 more source

A Scalable MapReduce Similarity Join Computation Using LSH

open access: yes, 2021
International audienceSimilarity joins are recognized to be among the most useful data process-ing and analysis operations. A similarity join is used to retrieve all data pairs whosedistances are smaller than a predefined threshold λ .In this paper, we ...
Rivault, Sébastien   +3 more
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Efficient String Edit Similarity Join Algorithm

open access: yes, 2017
String similarity join is a basic and essential operation in many applications. In this paper, we investigate the problem of string similarity join with edit distance constraints.
Gouda, Karam, Rashad, Metwally
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

DCJ-RNA - double cut and join for RNA secondary structures

open access: yesBMC Bioinformatics, 2017
Background Genome rearrangements are essential processes for evolution and are responsible for existing varieties of genome architectures. Many studies have been conducted to obtain an algorithm that identifies the minimum number of inversions that are ...
Ghada H. Badr, Haifa A. Al-aqel
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

DIMENSIONS OF LENIENCY POLICIES IN BRICS: A COMPARATIVE ANALYSIS OF INDIA, SOUTH AFRICA, BRAZIL AND RUSSIA

open access: yesBRICS Law Journal, 2016
A cartel is a group of similar, independent companies which join together to fix prices, limit production or share markets or customers among themselves.
D. Sharma
doaj   +1 more source

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