Results 131 to 140 of about 1,207,341 (288)

From Task Classification Towards Similarity Measures for Recommendation in Crowdsourcing Systems

open access: yes, 2017
Task selection in micro-task markets can be supported by recommender systems to help individuals to find appropriate tasks. Previous work showed that for the selection process of a micro-task the semantic aspects, such as the required action and the ...
Neitzel, Svenja   +2 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Application of Neutrosophic Similarity Measures in Covid-19. [PDF]

open access: yesAnn Data Sci, 2022
Das R, Mukherjee A, Tripathy BC.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Users' Rating Predictions Using Collaborating Filtering Based on Users and Items Similarity Measures. [PDF]

open access: yesComput Intell Neurosci, 2022
Nudrat S   +5 more
europepmc   +1 more source

Similarity measures

open access: yesScholarpedia, 2007
Daniel Ennis, F. Ashby
openaire   +1 more source

Random Markov-self-similar measures

open access: yesStochastic Processes and their Applications, 2002
Self-similar fractal sets in the Euclidean space are usually constructed by applying iteratively a fixed finite family of contractive mappings to a given initial set. Random self-similar sets are obtained if the contractive mappings are chosen randomly and independently at each step, following a prescribed distribution.
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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