In silico drug repositioning using deep learning and comprehensive similarity measures. [PDF]
Yi HC +5 more
europepmc +1 more source
The measurement of phonetic similarity [PDF]
openaire +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Mathematical modeling and AI based decision making for COVID-19 suspects backed by novel distance and similarity measures on plithogenic hypersoft sets. [PDF]
Ahmad MR, Afzal U.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Fermatean fuzzy copula aggregation operators and similarity measures-based complex proportional assessment approach for renewable energy source selection. [PDF]
Mishra AR +5 more
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Rapid Identification of H3N2 Influenza A Virus HA-Targeting Antibody Epitopes Driven by Computational Antibody Similarity Measures. [PDF]
Zhu Z +12 more
europepmc +1 more source
Human Tracking in Top-View Fisheye Images: Analysis of Familiar Similarity Measures via HOG and against Various Color Spaces. [PDF]
Talaoubrid H +3 more
europepmc +1 more source

