Results 181 to 190 of about 1,207,341 (288)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Novel similarity measures under complex pythagorean fuzzy soft matrices and their application in decision making problems. [PDF]

Sci Rep
Zeeshan M, Khan M, Shafqat R, Althobaiti A, Althobaiti S, Bedada TB.   +5 more
europepmc   +1 more source

Theoretical Infrared Spectra: Quantitative Similarity Measures and Force Fields. [PDF]

J Chem Theory Comput, 2020
Henschel H, Andersson AT, Jespers W, Mehdi Ghahremanpour M, van der Spoel D.   +4 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Cosine and cotangent similarity measures for intuitionistic fuzzy hypersoft sets with application in MADM problem. [PDF]

Heliyon
Naveed Jafar M, Saeed M, Saeed A, Ijaz A, Ashraf M, Jarad F.   +5 more
europepmc   +1 more source

Similarity measures and attribute selection for case-based reasoning in transcatheter aortic valve implantation. [PDF]

PLoS One, 2020
Feuillâtre H, Auffret V, Castro M, Lalys F, Le Breton H, Garreau M, Haigron P.   +6 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Using cross-recurrence quantification analysis to compute similarity measures for time series of unequal length with applications to sleep stage analysis. [PDF]

Sci Rep
Drews HJ, Felletti F, Kallestad H, Drews A, Scott J, Sand T, Engstrøm M, Heglum HSA, Vethe D, Salvesen Ø, Langsrud K, Morken G, Wallot S.   +12 more
europepmc   +1 more source

Organizing Tagged Knowledge: Similarity Measures and Semantic Fluency in Structure Mining. [PDF]

J Mech Des N Y, 2020
Sexton R, Fuge M.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source