Results 211 to 220 of about 324,674 (263)
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
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IEEE Transactions on Pattern Analysis and Machine Intelligence, 1999
With complex multimedia data, we see the emergence of database systems in which the fundamental operation is similarity assessment. Before database issues can be addressed, it is necessary to give a definition of similarity as an operation. We develop a similarity measure, based on fuzzy logic, that exhibits several features that match experimental ...
Simone Santini
exaly +2 more sources
With complex multimedia data, we see the emergence of database systems in which the fundamental operation is similarity assessment. Before database issues can be addressed, it is necessary to give a definition of similarity as an operation. We develop a similarity measure, based on fuzzy logic, that exhibits several features that match experimental ...
Simone Santini
exaly +2 more sources
2005 Seventh IEEE Workshops on Applications of Computer Vision (WACV/MOTION'05) - Volume 1, 2005
Quantitative evaluation and comparison of image segmentation algorithms is now feasible owing to the recent availability of collections of hand-labeled images. However, little attention has been paid to the design of measures to compare one segmentation result to one or more manual segmentations of the same image.
Ranjith Unnikrishnan, Martial Hebert
openaire +1 more source
Quantitative evaluation and comparison of image segmentation algorithms is now feasible owing to the recent availability of collections of hand-labeled images. However, little attention has been paid to the design of measures to compare one segmentation result to one or more manual segmentations of the same image.
Ranjith Unnikrishnan, Martial Hebert
openaire +1 more source
A statistical similarity measure
Proceedings of the 10th annual international ACM SIGIR conference on Research and development in information retrieval - SIGIR '87, 1987Within the framework of the vector space models, a statistical similarity measure between document and query is proposed. In this approach the assumption that term (or atomic) vectors are pairwise orthogonal is not required. In addition, it provides a natural and consistent interpretation of term occurrence frequencies obtained from autoindexing.
S. K. Michael Wong, Yiyu Yao
openaire +2 more sources
Neural Processing Letters, 1997
This paper concerns with the ART1 (Adaptive Resonance Theory 1) in Neural Network. Important features of ART1 are similarity measure (criterion), vigilance parameter (r), and their function to classify the input patterns. Experimental results show that the similarity measure as designed originally does not increase the number of categories with the ...
Ei Ei Khin +2 more
openaire +1 more source
This paper concerns with the ART1 (Adaptive Resonance Theory 1) in Neural Network. Important features of ART1 are similarity measure (criterion), vigilance parameter (r), and their function to classify the input patterns. Experimental results show that the similarity measure as designed originally does not increase the number of categories with the ...
Ei Ei Khin +2 more
openaire +1 more source