Results 31 to 40 of about 3,878,669 (209)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

A new similarity measure for rankings obtained in MCDM problems using different normalization techniques [PDF]

open access: yes
The paper presents an analysis of the impact of normalization techniques on the ranking of alternatives obtained using the combined compromise solution (CoCoSo) method.
Kacprzak, Dariusz
core   +3 more sources

Similarity of sensorimotor experience as a measure of the relatedness among the meanings

open access: yes, 2023
PDP models of lexical ambiguity (Rodd, 2018) see the word meaning as distributed in the pattern of activation of basic units, the patterns being more similar in the case of related senses of the polysemous words (paper), than in the case of unrelated ...
Filipović Đurđević, Dušica   +1 more
core   +1 more source

Image Similarity Metrics in Image Registration [PDF]

open access: yes, 2010
Measures of image similarity that inspect the intensity probability distribution of the images have proved extremely popular in image registration applications. The joint entropy of the intensity distributions and the marginal entropies of the individual
Melbourne, A, Ridgway, G, Hawkes, DJ
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

New similarity measures for ligand-based virtual screening [PDF]

open access: yes, 2017
The process of drug discovery using virtual screening techniques relies on “molecular similarity principle” which states that structurally similar molecules tend to have similar physicochemical and biological properties in comparison to other dissimilar ...
Himmat, Mubarak Hussein Ibrahim
core  

HESML V1R5 Java software library of ontology-based semantic similarity measures and information content models

open access: yes, 2021
This dataset introduces HESML V1R5 which is the fifth release of the Half-Edge Semantic Measures Library (HESML) detailed in [13]. HESML V1R5 is a linearly scalable and efficient Java software library of ontology-based semantic similarity measures and ...
Lara-Clares, Alicia   +2 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

XML Schema Element Similarity Measures: A Schema Matching Context [PDF]

open access: yes, 2009
In this paper, we classify, review, and experimentally compare\ud major methods that are exploited in the definition, adoption, and\ud utilization of element similarity measures in the context of XML schema\ud matching.
Nayak, Richi   +5 more
core   +1 more source

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