Results 161 to 170 of about 1,243,483 (265)

jdispatcher-viewers: interactive visualizations of sequence similarity search results and domain predictions. [PDF]

Bioinform Adv
Madeira F, Lee J, Madhusoodanan N, Eusebi A, Niewielska A, Butcher S.   +5 more
europepmc   +1 more source

SIMBSIG: Similarity search and clustering for biobank-scale data

, 2022
Adamer MF, Roellin E, Bourguignon L, Borgwardt K.   +3 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Leveraging a foundation model zoo for cell similarity search in oncological microscopy across devices. [PDF]

Front Oncol
Kalweit G, Klett A, Silvestrini P, Rahnfeld J, Naouar M, Vogt Y, Infante D, Berger R, Duque-Afonso J, Hartmann TN, Follo M, Bodurova-Spassova E, Lübbert M, Mertelsmann R, Boedecker J, Ullrich E, Kalweit M.   +16 more
europepmc   +1 more source

Identification of a novel dual-target scaffold for 3CLpro and RdRp proteins of SARS-CoV-2 using 3D-similarity search, molecular docking, molecular dynamics and ADMET evaluation. [PDF]

J Biomol Struct Dyn, 2021
Aouidate A, Ghaleb A, Chtita S, Aarjane M, Ousaa A, Maghat H, Sbai A, Choukrad M, Bouachrine M, Lakhlifi T.   +9 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Protein domain embeddings for fast and accurate similarity search. [PDF]

Genome Res
Iovino BG, Tang H, Ye Y.
europepmc   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source

Foldclass and Merizo-search: scalable structural similarity search for single- and multi-domain proteins using geometric learning. [PDF]

Bioinformatics
Kandathil SM, Lau AM, Buchan DWA, Jones DT.   +3 more
europepmc   +1 more source