Results 171 to 180 of about 453,861 (266)

Application of machine learning to nanomaterial design with silver nanoprisms. [PDF]

Discov Nano
Richard C, Pichon PA, Nováková J, Najafabadi NI, Sá J.   +4 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Uncovering latent profiles of multidimensional work attitudes: cross-cultural evidence from Poland and Vietnam. [PDF]

Front Psychol
Jurek P, Lac AT, Le BN, Olech M, Różycka-Tran J.   +4 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Boosting the Diversity of a Similarity-Aware Genetic Algorithm Using a Siamese Network for Optimized S-Box Generation. [PDF]

Entropy (Basel)
Khaja IA, Ahmad M, Maghrabi LA.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Differentiation of disaccharide isomers <i>via</i> diagnostic-ion-weighted spectral library searching using data from tandem MS analysis of chloride adducts.

Analyst
Xu S, Acharya SR, Speidel RM, Badu-Tawiah AK.   +3 more
europepmc   +1 more source

An Effective Non-Rigid Registration Approach for Ultrasound Images Based on the Improved Variational Model of Intensity, Local Phase Information and Descriptor Matching. [PDF]

J Imaging
Zhang K, Xing J, Xiao Q.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

MechFind: a computational framework for de novo prediction of enzyme mechanisms. [PDF]

Nat Commun
Hartley AD, Upadhyay V, Boorla VS, Maranas CD.   +3 more
europepmc   +1 more source