Results 211 to 220 of about 1,077,142 (303)

Genetic‐Proteomic Integration Identifies Predictive Plasma Proteins for Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) develops after a prolonged preclinical phase. Identifying circulating biomarkers that capture this early biology can improve risk stratification and guide intervention. We aimed to identify plasma proteins driving MS susceptibility using large‐scale proteogenomic integration and to evaluate their prediagnostic ...
Yuan Ding, Dylan Hamitouche, Simon Thebault, Patrick Kearns, Ahmed Abdelhak, Adil Harroud   +5 more
wiley   +1 more source

Photocatalytic Lignin Depolymerization and Cross‐Coupling With Alcohols to Produce Unsymmetric Aromatic Diols

Angewandte Chemie, EarlyView.
A photocatalytic approach for efficient one‐pot direct lignin depolymerization and subsequent cross‐coupling with alcohols for the production of unsymmetrical aromatic diols has been demonstrated. ABSTRACT Conversion of lignin into chemical products typically involves two separate steps, such as depolymerization and subsequent upgrading of monomers ...
Hongji Li, Jialing Ma, Xiaoling Wan, Yumei Liu, Chaofeng Zhang, Xiaoqin Si, Xiaojun Shen, Rajenahally V. Jagadeesh   +7 more
wiley   +2 more sources

Uncovering thousands of endosymbiont DNA transfer events within single cockroach genomes. [PDF]

Proc Natl Acad Sci U S A
Ewart KM, Adams MWD, Zhang Z, Baker L, Fujiwara K, Hayashi Y, Featherstone LA, Lu OL, Helbling JES, Moral M, Maekawa K, Rose H, Jex A, Ho SYW, Lo N.   +14 more
europepmc   +1 more source

Carbohydrate Physicochemical Properties: The Innate Hydrogen Bond Donating Capacities of α‐Glucoside and α‐Galactoside Alcohol Groups

Angewandte Chemie, EarlyView.
Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar, Zhong Wang, Krunal Patel, Branko De Baets, Anaïs Goupille, Davy Sinnaeve, Eric Renault, Jean‐Yves Le Questel, Bruno Linclau   +8 more
wiley   +2 more sources

Correction: Bis(amidophenolate)-supported pnictoranides: Lewis acid-induced electromerism in a bismuth complex. [PDF]

Chem Sci
Karnbrock SBH, Köster JF, Becker I, Golz C, Meyer F, Gimferrer M, Alcarazo M.   +6 more
europepmc   +1 more source

Optimize Before You Synthesize—Enhancing the Ionic Conductivity of Li7SiPS8 Using Bayesian Optimization

Angewandte Chemie, EarlyView.
Bayesian optimization was used to optimize the synthesis parameters of the solid electrolyte Li7SiPS8$\mathrm {Li}_7\mathrm {SiPS}_8$ in order to increase the ionic conductivity. After only 32 iterations, the ionic conductivity was successfully increased from 2 to 7 mS cm−1$\mathrm {cm}^{-1}$ at 25∘C$^\circ\mathrm {C}$, while synthesis temperature and ...
Lucas G. Balzat, Robert Calaminus, Yinghan Zhao, Kristina Gjorgjevikj, Igor Moudrakovski, Simon Krause, Arnd Koeppe, Britta Nestler, Bettina V. Lotsch   +8 more
wiley   +2 more sources

microRNA profiles in slow and fast skeletal muscle fibers. [PDF]

Physiol Genomics
Simon L.
europepmc   +1 more source

CSAKD: Determining Absolute Ligand Affinities From 19F NMR Chemical Shift Anisotropy

Angewandte Chemie, EarlyView.
Affinity determination is crucial in drug discovery, yet remains difficult for weakly binding fragments. We introduce chemical shift anisotropy KD$K_{\text{D}}$ (CSAKD) by 19F$^{19}{\rm F}$ NMR relaxation experiments, a titration‐free method that requires no isotopic labeling.
Simon H. Rüdisser, Gabriela Stadler, Alvar D. Gossert   +2 more
wiley   +2 more sources

Drug cue enhances response conflict and reduces conflict adaptation in methamphetamine addiction. [PDF]

Psychol Res
Xu Y, Lu Y, Wang L.
europepmc   +1 more source

Herbert A. Simon

, 1989
openaire   +1 more source