Results 31 to 40 of about 478,846 (274)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Biodegradable 3D‐Printable and Coatable Antifouling Composites for Marine Applications
Advanced Functional Materials, EarlyView.Marine biofouling damages submerged surfaces and raises greenhouse gas emissions. Biodegradable antifouling biocomposites were developed by hot‐mixing beeswax, Tween 80, and calcium stearate or stearic acid. Adjusting the component ratio enables processing via hot‐pressing, 3D‐printing, or dip‐coating.
Gabriele Corigliano +17 more
wiley +1 more source
PLANT, Stephen, Simone Weil (traducción de María Teresa Solana), Herder, Barcelona., 1997, 121 pp.
Revista de Filosofía Universidad Iberoamericana, 1998 Este libro, de ágil lectura, nos introduce al pensamiento de Simone Weil (1909-1943) desde una triple perspectiva que nos permite aquilatar la riqueza de su filosofía teológica así como su rara capacidad para llegar, de manera clara y directa, al ...
María Dolores Illescas Nájera
doaj +1 more source
Advanced Materials, EarlyView.Vertical organic electrochemical transistors (vOECTs) are limited in speed by ion‐impermeable metal electrodes that slow ion injection. Using ion‐permeable PBFDO top electrodes allows direct vertical ion injection into BBL channels, achieving high current densities (>400 A cm−2), large on/off ratios (>106), and ultrafast switching in 28 µs. This sets a
Han‐Yan Wu +14 more
wiley +1 more source
Qu'aurait pensé Simone Weil de l'encyclique Laudato si' ?
, 2017 International audienceL’encyclique « Laudato si’ », « sur la sauvegarde de la maison commune », publiée par le pape en juin 2015 et adressé à « toutes les personnes de bonne volonté », a, de par l'urgence des questions abordées et le style employé ...
Rey, Olivier
core +3 more sources
Resonant Domain Wall Dynamics in a Three‐Dimensional Magnetic Nano Double Helix
Advanced Materials, EarlyView.3D magnetic nanostructures promise exciting possibilities for magnetization dynamics. However, experimental realizations remain scarce. In nanoprinted cobalt double helices, time‐resolved X‐ray microscopy reveals harmonic domain wall dynamics. Simulations identify the mode and additional higher‐frequency resonances, revealing a rich dynamic landscape ...
Pamela Morales‐Fernández +15 more
wiley +1 more source
Asparkía, 2007 RESUMEN: Este artículo analiza el sexto libro de la poeta canadiense Sarah Klassen, Simone Weil: Songs of Hunger and Love (1999), una colección de poemas y breves piezas en prosa donde la autora presta su primera persona a Simone Weil, filósofa francesa ...
Nieves Pascual Soler
doaj