Results 81 to 90 of about 3,032,997 (214)

Variation in blood culture testing in children hospitalized with three common infections

Journal of Hospital Medicine, EarlyView.
Abstract Background Routine blood culture (BCx) testing in uncomplicated community‐acquired pneumonia (CAP), skin and soft tissue infections (SSTI), and urinary tract infections (UTI) has demonstrated low clinical utility. Objectives To evaluate hospital‐level BCx testing trends and their association with clinical outcomes for children hospitalized ...
Smit Shah, Jennifer L. Goldman, Matt Hall, John R. Stephens, Jillian M. Cotter, Samantha A. House, Matthew J. Molloy, Michelle Polich, Michael J. Steiner, Michael J. Tchou, Ronald J. Teufel II, Irma T. Ugalde, Andrew G. Yu, Jessica L. Markham   +13 more
wiley   +1 more source

Illness in Children Presenting to the Emergency Department After International Travel: A 10‐Year Retrospective Analysis From the University Hospital of Helsinki, Finland

Acta Paediatrica, EarlyView.
ABSTRACT Aim We characterized infections after international travel and identified predictors of severe infection to refine management. Methods We conducted a retrospective cross‐sectional analysis of children aged 0–18 years presenting to Helsinki University Hospital Emergency Department within 90 days of international travel between January 1, 2015 ...
Tuula Pelkonen, Svetlana Vakkilainen
wiley   +1 more source

Deep Phenotyping in ReNU Syndrome Identifies a Recognizable Age‐Dependent Clinical Trajectory

Clinical Genetics, EarlyView.
Longitudinal evaluation of 11 individuals with ReNU syndrome revealed an age‐dependent multisystem trajectory. This longitudinal description may help clinicians anticipate changing needs in feeding, growth, neurological, visual, communication, behavioral, and orthopedic care. ABSTRACT Pathogenic variants in the noncoding gene RNU4‐2 cause ReNU syndrome,
Nadja Pekkola Pacheco, Malin Kvarnung, Anna Hammarsjö, Daniel Nilsson, Bianca Tesi, Britt Marie Anderlid, Giedre Grigelioniene, Maria Johansson Soller, Liselot van der Laan, Charlotte Willfors, Charlotta Ingvoldstad Malmgren, Anna Lindstrand, Tommy Stödberg, Ann Nordgren, Angelica Maria Delgado‐Vega   +14 more
wiley   +1 more source

Five Years Study of Recurrent Febrile Seizure Risk Factors [PDF]

, 2017
Background: Nearly one-third of febrile seizure patients suffered recurrent febrile seizures.  Several risk factors contribute to this recurrence, namely young age, family history of febrile seizures, low body temperature and rapid duration of fever ...
Nurhayati, Titing, Ausi Indriani, Titing Nurhayati, Indriani, Ausi, Nelly Amalia Risan, Risan, Nelly Amalia   +5 more
core   +1 more source

Challenges in Gene‐Directed Therapies for Rare Neurodevelopmental Disorders Using HNRNPU as an Exemplar

Clinical Genetics, EarlyView.
Beyond diagnosing rare neurodevelopmental disorders like HNRNPU‐RNDD, developing gene‐directed therapies requires overcoming complex hurdles, including spatial, developmental, and cell‐type constraints. Addressing these requires understanding the molecular effects of dosage and chromatin dynamics to deliver precise, effective treatments.
Daniel Aiyedun, Susan F. Rogers, Doaa M. Taha, Meena Balasubramanian   +3 more
wiley   +1 more source

Foraminal subependymal nodules and subependymal giant cell astrocytoma in children with tuberous sclerosis

Developmental Medicine &Child Neurology, EarlyView.
We studied 128 TSC referred to our tertiary centre between 2012 and 2024, with at least one brain imaging before 18 years, before neurosurgical or mTOR inhibitor treatment, and at least one fSEN. Median age at first and last imaging was 3 years 2 months and 12 years. Longitudinal fSEN evolution with age identified three growth patterns: non‐growing (71%
Sofia Ferri, Sara Cabet, Nicole Chemaly, Jacques Laschet, Thomas Blauwblomme, Nathalie Boddaert, Rima Nabbout   +6 more
wiley   +1 more source

RCC1 neuropathy mimics childhood axonal Guillain–Barré syndrome with variable clinical severity and survival

Developmental Medicine &Child Neurology, EarlyView.
We present 10 patients who presented with acute onset axonal neuropathy following infection, mimicking childhood axonal Guillain–Barré syndrome. We review phenotypes, undertake survival analysis, and assess function of novel RCC1 variants in vitro. Abstract Aim To assess the phenotype and genotype of 10 new patients with biallelic RCC1 variants who ...
Han Zhang, Beril Din, John H. McDermott, RCC1 Neuropathy Study Group, Adam Jackson, Halil Tuna Akar, Ali Dursun, Riza Koksal‐Ozgul, Reza Sadjadi, Lauren Politica, Stephan Zuchner, Reza Maroofian, Usman Ali, Dudu Turkyilmaz, Jawadur Rahman, Hasan Bas, Khalid Hussain, Khalid A Fakhro, Aljazi Al‐Maraghi, Annemarie CS Knijnenburg, Monique Engel, Debby Hellebrekers, Heike Losch, Sietse M Aukema, Marlene Kullik, Christoph Geier, Raymond T. O'Keefe, William G. Newman, J. Robert Harkness   +28 more
wiley   +1 more source

Risk of Febrile Seizure Recurrence and Outcome

, 1998
The influence of febrile episodes, a risk factor for recurrence of febrile seizures, and outcome in 180 children followed prospectively after their first febrile seizure, were studied at the University of Oulu ...
J Gordon Millichap, Millichap, J. Gordon
core   +1 more source

Consent, Trust, and Sexual Ethics

Philosophical Perspectives, EarlyView.
ABSTRACT No one describes a passionate night using the language of consent. Partners in long‐term relationships rarely think of intimacy in terms of permission. If consent is absent precisely when things go well, why does it dominate sexual ethics? Critics have pressed this challenge but have failed to explain why consent is irrelevant rather than ...
Elise Woodard
wiley   +1 more source

Validity of Serum Sodium and Calcium Screening in Children [PDF]

Acta Medica Iranica, 2009
Febrile convulsion (FC) is the most common seizure disorder in young children. Different predisposing factors have been suggested to enhance the susceptibility to febrile seizure and its recurrence.
Azar Nickavar, Hosein Hasanpour, Kambiz Sotoudeh   +2 more
doaj   +1 more source