Results 171 to 180 of about 6,208,817 (342)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Harmonizing results of ataxia rating scales: mFARS, SARA, and ICARS
Abstract The ever‐increasing body of ataxia research provides opportunities for large‐scale meta‐analyses, systematic reviews, and data aggregation. Because multiple standardized scales are used to quantify ataxia severity, harmonization of these measures is necessary for quantitative data pooling. We applied the modified Friedreich Ataxia Rating Scale
Christian Rummey+5 more
wiley +1 more source
Triangle groups and finite simple groups
This thesis contains a study of the spaces of homomorphisms from hyperbolic triangle groups to finite groups of Lie type which leads to a number of deterministic, asymptotic, and probabilistic results on the (p1, p2, p3)-generation problem for finite groups of Lie type.
Marion, Claude Miguel Emmanuel+1 more
openaire +4 more sources
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo+2 more
wiley +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
A counterexample for the conjecture of finite simple groups [PDF]
In this note we provide some counterexamples for the conjectures of finite simple groups, one of the conjectures said "all finite simple groups $G$ can be determined using their orders $|G|$ and the number of elements of order $p$, where $p$ the largest prime divisor of $|G|$".
arxiv
A new proof of E. Cartan’s theorem on the topology of semi-simple groups [PDF]
G. D. Mostow
openalex +1 more source
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
ON A GROUP EXTENSION INVOLVING THE SPORADIC JANKO GROUP \(J_{2}\)
Using the electronic Atlas of Wilson [21], the group J_2 has an absolutely irreducible module of dimension 6 over F_4. Therefor a split extension group of the form 4^6:J_2:= \bar{G} exists.
Ayoub B. M. Basheer
doaj +1 more source
Demi-groupes inversifs et demi-groupes réunions de demi-groupes simples [PDF]
R. Croisot
openalex +1 more source