Parent‐to‐Child Information Disclosure in Pediatric Oncology
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor +12 more
wiley +1 more source
Thesauri are Knowledge Organization Systems (KOS), that arise from the consensus of wide communities. They have been in use for many years and are regularly updated.
M. Mercedes Martinez-Gonzalez +1 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Comparing human and automatic thesaurus mapping approaches in the agricultural domain [PDF]
Knowledge organization systems (KOS), like thesauri and other controlled vocabularies, are used to provide subject access to information systems across the web.
Caracciolo, Caterina +5 more
core +5 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Exploring a Case of Knowledge Infrastructure in the Pharmaceutical Environment - A case study at AstraZeneca [PDF]
Vårterminen 2006Knowledge today tends to be an organization’s prime tool in order to compete on the business market. For companies like AstraZeneca where research is one of the corner stones there must be an easy way for accessing and sharing knowledge.
Engman, Johan, Holmberg, Martin
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PREVENTION OF RABIES DISEASE IN THE WORKING AREA OF PUBLIC HEALTH SERVICE OF EAST TOMONI
Background: Rabies is a deadly disease that is transmitted from animals to humans and attacks the central nervous system (WHO, 2016). Data reported by the World Animal Health Organization (OIE) revealed that the global human death rate due to rabies is ...
Armawati Abidin, Anas Budi
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Complex Systems Science: Dreams of Universality, Reality of Interdisciplinarity [PDF]
Using a large database (~ 215 000 records) of relevant articles, we empirically study the "complex systems" field and its claims to find universal principles applying to systems in general. The study of references shared by the papers allows us to obtain
Bastian M. +9 more
core +4 more sources

