Results 31 to 40 of about 1,281,981 (325)

On the Links of Simple Singularities, Simple Elliptic Singularities and Cusp Singularities

Demonstratio Mathematica, 2015
This is a survey article about the study of the links of some complex hypersurface singularities in ℂ3 . We study the links of simple singularities, simple elliptic singularities and cusp singularities, and the canonical contact structures on them. It is
Kasuya Naohik
doaj   +1 more source

Orthogonal polynomials of compact simple Lie groups: Branching rules for polynomials

, 2010
Polynomials in this paper are defined starting from a compact semisimple Lie group. A known classification of maximal, semisimple subgroups of simple Lie groups is used to select the cases to be considered here.
Nesterenko, Maryna, Patera, Jiri, Szajewska, Marzena, Tereszkiewicz, Agnieszka   +3 more
core   +1 more source

On the Unification of Gauge Symmetries in Theories with Dynamical Symmetry Breaking

, 2005
We analyze approaches to the partial or complete unification of gauge symmetries in theories with dynamical symmetry breaking. Several types of models are considered, including those that (i) involve sufficient unification to quantize electric charge ...
Neil D. Christensen, Robert Shrock, T. Appelquist   +2 more
core   +1 more source

Disjointness of a Simple Matrix Lie Group and Its Lie Algebra

Vietnam Journal of Mathematics, 2023
Let $G$ be a connected closed subgroup of $\mathrm{GL}_n(\mathbb{C})$ which is simple as a Lie group and which acts irreducibly on $\mathbb{C}^n$. Regarding both $G$ and its Lie algebra $\mathfrak{g}$ as subsets of $M_n(\mathbb{C})$, we have $G\cap \mathfrak{g}\neq\emptyset$ if and only if $G$ is a classical group and $\mathbb{C}^n$ is a minuscule ...
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Compact Lie Groups, Generalised Euler Angles, and Applications

Universe, 2022
This is mainly a review of an intense 15-year long collaboration between the authors on explicit realisations of compact Lie groups and their applications.
Sergio Luigi Cacciatori, Antonio Scotti
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source