Results 51 to 60 of about 321 (215)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Poisson-Lie analogues of spin Sutherland models

open access: yesNuclear Physics B, 2019
We present generalizations of the well-known trigonometric spin Sutherland models, which were derived by Hamiltonian reduction of ‘free motion’ on cotangent bundles of compact simple Lie groups based on the conjugation action.
L. Fehér
doaj   +1 more source

A product theorem in simple Lie groups [PDF]

open access: yesGeometric and Functional Analysis, 2015
We prove a discretized Product Theorem for general simple Lie groups, in the spirit of Bourgain's Discretized Sum-Product Theorem.
openaire   +2 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

η and λ deformations as E-models

open access: yesNuclear Physics B, 2015
We show that the so-called λ deformed σ-model as well as the η deformed one belong to a class of the E-models introduced in the context of the Poisson–Lie-T-duality. The λ and η theories differ solely by the choice of the Drinfeld double; for the λ model
Ctirad Klimčík
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Superuniversality of Superdiffusion

open access: yesPhysical Review X, 2021
Anomalous finite-temperature transport has recently been observed in numerical studies of various integrable models in one dimension; these models share the feature of being invariant under a continuous non-Abelian global symmetry.
Enej Ilievski   +4 more
doaj   +1 more source

On the Fundamental Group of a Simple Lie Group [PDF]

open access: yesNagoya Mathematical Journal, 1970
Let G be a simply connected simple Lie group and C the center of G, which is isomorphic with the fundamental group of the adjoint group of G. For an element c of C, an element x of the Lie algebra g of G is called a representative of c in g if exp x = c.
openaire   +3 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

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