Results 51 to 60 of about 1,803,467 (337)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Journal of the Mathematical Society of Japan, 2016 For a compact simple Lie group $G$, we show that the element $[G, \mathcal{L}] \in \pi^S_*(S^0)$ represented by the pair $(G, \mathcal{L})$ is zero, where $\mathcal{L}$ denotes the left invariant framing of $G$. The proof relies on the method of E. Ossa [Topology, 21 (1982), 315–323].
openaire +3 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Gaussian Cubature Arising from Hybrid Characters of Simple Lie Groups [PDF]
, 2012 Lie groups with two different root lengths allow two ‘mixed sign’ homomorphisms on their corresponding Weyl groups, which in turn give rise to two families of hybrid Weyl group orbit functions and characters.
R. Moody, L. Motlochová, J. Patera
semanticscholar +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Compact Lie Groups, Generalised Euler Angles, and Applications
Universe, 2022 This is mainly a review of an intense 15-year long collaboration between the authors on explicit realisations of compact Lie groups and their applications.
Sergio Luigi Cacciatori, Antonio Scotti
doaj +1 more source
From Loop Groups to 2-Groups [PDF]
, 2005 We describe an interesting relation between Lie 2-algebras, the Kac-Moody central extensions of loop groups, and the group String(n). A Lie 2-algebra is a categorified version of a Lie algebra where the Jacobi identity holds up to a natural isomorphism ...
Baez, John C. +3 more
core +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
AIMS MathematicsIn this article, the investigation into the Lie symmetry algebra of the geodesic equations of the canonical connection on a Lie group was continued. The key ideas of Lie group, Lie algebra, linear connection, and symmetry were quickly reviewed. The focus
Nouf Almutiben +3 more
doaj +1 more source