Results 111 to 120 of about 18,851,418 (301)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Discrete Finger Response Latencies in a Simple Reaction Time Task

, 1991
The present study evaluated the potential for neuroanatomical factors to operate in a simple reaction time task. That is, response latencies were recorded for all ten fingers on a Donders' A reaction time task. Two finger-placement conditions were used,
Loe M. A. Van Veggel, Jos J. Adam
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Facile synthesis of copper nanostructures through simple replacement reaction

, 2015
Copper, an old material, is still extensively used nowadays. In this paper, through extremely simple replacement reaction approach, we synthesized various copper nanostructures under ambient atmosphere at room temperature.
Wei FN(魏发南), Liu LQ(刘连庆), Li LH(李龙海)   +2 more
core  

Composite reaction time and variability correlate with whole-brain white-matter characteristics

The relationship between processing speed and brain network characteristics has been widely studied, yet the results remain inconsistent. While many studies have linked processing speed to the microstructure of white matter, discrepancies arise due to ...
Sumner, Petroc, Hedge, Craig, Jones, Derek K., Laguna, Pedro Luque, Messaritaki, Eirini, McNabb, Carolyn B.   +5 more
core   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Optimal simple targeting rules for small open economies [PDF]

This paper solves for optimal policy rules in a stylized small open economy model under a spectrum of targeting regimes. These policy reaction functions are presented as feedback rules highlighting the dominant state variables in each rule.
Richard Dennis
core  

The impact of total sleep deprivation upon cognitive functioning in firefighters

Neuropsychiatric Disease and Treatment, 2018
Sławomir Kujawski,1 Joanna Słomko,1 Małgorzata Tafil-Klawe,2 Monika Zawadka-Kunikowska,1 Justyna Szrajda,1 Julia L Newton,3 Paweł Zalewski,1 Jacek J Klawe1 1Department of Hygiene, Epidemiology and Ergonomics, Nicolaus Copernicus University, Toruń ...
Kujawski S, Słomko J, Tafil-Klawe M, Zawadka-Kunikowska M, Szrajda J, Newton JL, Zalewski P, Klawe JJ   +7 more
doaj  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source