Results 71 to 80 of about 18,851,418 (301)

Relative performance of the two hands in simple and choice reaction time tasks

Brazilian Journal of Medical and Biological Research, 2014
There is evidence that the left hemisphere is more competent for motor control than the right hemisphere. This study investigated whether this hemispheric asymmetry is expressed in the latency/duration of sequential responses performed by the left and/or
M. Nisiyama, L.E. Ribeiro-do-Valle
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Effect of loud music and active telephonic conversation on simple visual reaction time

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: In India, there is at least one death for every 4 min due to road traffic accidents (RTA’s) (1.37, 423 deaths in a year), of which 77.5% are due to fault of drivers.
Pradeep Reddy Srikaram, Ambareesha K, Kasthuri Bai P   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A Serial Simple Reaction-Time Circuit

, 1963
A description of a simple reaction time circuit which eliminates the recording of anticipatory responses as non-anticipatory in nature and yet preserves the integrity of the interval of time between the response and the onset of the signal.
C. L. Bell, P. D. Mc Cormack
core   +1 more source

Simple visual reaction time in sickle cell disease patients of pediatric age group

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Reaction time (RT) test can be simple or choice or recognition type. RT test has been widely used in literature, but the changes seen, if any is not documented in pediatric age group of sickle cell patients.
Arunita Jagzape, Tushar Jagzape, Vijay Deshpande   +2 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Ring closing reaction in diarylethene captured by femtosecond electron crystallography [PDF]

, 2013
The photoinduced ring closing reaction in diarylethene, which serves as a modelsystem for understanding reactive crossings through conical intersections, was directly observed with atomic resolution using femtosecond electron diffraction.
Liu, Lai Chung, Jean-Ruel, H., Cooney, R., Liu, L., Miller, R., Gao, Meng, Miller, R. J. Dwayne, Kochman, Michal A., Cooney, Ryan R., Morrison, C., Lu, Cheng, Jean-ruel, Hubert, Gao, M., Morrison, Carole A., Lu, C., Kochman, M.   +15 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Reliability of computerized eye-tracking reaction time tests in non-athletes, athletes, and individuals with traumatic brain injury [PDF]

, 2018
Background: Eye tracking technologies and methodologies have advanced significantly in recent years. Specifically, the use of eye tracking to quantitatively measure oculomotor and psychophysiological constructs is gaining momentum. Reaction time has been
Lange, Belinda, Hunfalvay, Melissa, Murray, Nick, Roberts, Claire-Marie, Bolte, Takumi   +4 more
core